SAB2501042
Anti-TIP30/CC3 antibody produced in goat
affinity isolated antibody, buffered aqueous solution
동의어(들):
Anti-HIV-1 Tat interactive protein 2, Anti-HTATIP2, Anti-Tat-interacting protein (30 kDa)
로그인조직 및 계약 가격 보기
크기 선택
100 μG
₩670,611
₩670,611
예상 입고일2025년 5월 19일세부사항
기존과 동일한 품질을 인하된 가격으로 - 어려운 예산 상황을 머크와 함께 극복하세요
모든 사진(1)
크기 선택
보기 변경
100 μG
₩670,611
About This Item
UNSPSC 코드:
12352203
NACRES:
NA.41
₩670,611
예상 입고일2025년 5월 19일세부사항
기존과 동일한 품질을 인하된 가격으로 - 어려운 예산 상황을 머크와 함께 극복하세요
추천 제품
생물학적 소스
goat
결합
unconjugated
항체 형태
affinity isolated antibody
항체 생산 유형
primary antibodies
클론
polyclonal
양식
buffered aqueous solution
종 반응성
human
기술
indirect ELISA: suitable
western blot: suitable
UniProt 수납 번호
배송 상태
dry ice
저장 온도
−20°C
타겟 번역 후 변형
unmodified
유전자 정보
human ... HTATIP2(10553)
일반 설명
Tat-interacting protein 30 (TIP30), also called CC3/ HIV-1 tat interactive protein 2 (HTATIP2), is a putative tumor suppressor. It is encoded by the gene mapped to human chromosome 11p15.1. TIP30 is primarily localized in cytoplasm and it belongs to short-chain dehydrogenases/reductase (SDR) family. The encoded protein is extensively expressed in various human tissues, such as the heart, brain, lung, kidney and pancreas.
면역원
Peptide with sequence AETEALSKLREDFR-C from the N Terminus of the protein sequence according to NP_006401.
생화학적/생리학적 작용
Tat-interacting protein 30 (TIP30) has an ability to promote apoptosis and suppress metastasis and angiogenesis. It is also implicated in regulation of DNA repair and tumor cell metabolism. Down-regulated expression of the gene is associated with the development of various cancers, including melanoma, breast cancer, neuroblastoma, glioblastoma, colon cancer, lung cancer and hepatocellular carcinoma. Elevated expression of the gene in glioma cells inhibits tumor proliferation, metastasis and migration. Thus, TIP30 can be considered as a potent target for treating glioma patients.
특징 및 장점
Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.
물리적 형태
Supplied at 0.5 mg/mL in Tris saline with 0.02% sodium azide and 0.5% bovine serum albumin.
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신호어
Warning
유해 및 위험 성명서
예방조치 성명서
Hazard Classifications
Eye Irrit. 2 - Skin Irrit. 2
Storage Class Code
10 - Combustible liquids
WGK
WGK 2
Flash Point (°F)
Not applicable
Flash Point (°C)
Not applicable
가장 최신 버전 중 하나를 선택하세요:
TIP30 Deficiency Increases Susceptibility to Tumorigenesis
Ito M, et al.
Cancer Research, 63(24), 8763-8767 (2003)
Overexpression of TIP30 inhibits the growth and invasion of glioma cells
Hu Y, et al.
Molecular Medicine Reports, 13(1), 605-612 (2016)
TIP30: a novel tumor-suppressor gene.
Yu X, et al.
Oncology Research, 22(5-6), 339-348 (2015)
Tat-Interacting Protein 30 (TIP30) Expression Serves as a New Biomarker for Tumor Prognosis: A Systematic Review and Meta-Analysis
Xu T, et al.
PLoS ONE, 11(12), e0168408-e0168408 (2016)
Xin Tong et al.
The American journal of pathology, 174(5), 1931-1939 (2009-04-08)
The HIV Tat-interacting protein (TIP30), also called CC3 or HTIP2, is encoded by Tip30, a putative tumor-suppressor gene located on human chromosome 11p15.1. In this study, we investigated the role of TIP30 in the progression and metastasis of lung cancer.
활성 필터
자사의 과학자팀은 생명 과학, 재료 과학, 화학 합성, 크로마토그래피, 분석 및 기타 많은 영역을 포함한 모든 과학 분야에 경험이 있습니다..
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