추천 제품
특이성
Bcl-2
면역원
KLH-conjugated, synthetic peptide corresponding to amino acids 41-54 (C-GAAPAPGIFSSQPG) of human Bcl-2
애플리케이션
Research Category
Apoptosis & Cancer
Apoptosis & Cancer
Research Sub Category
BCL2 & Inhibition
BCL2 & Inhibition
This Anti-Bcl-2 Antibody, clone AW604 is validated for use in IP, WB for the detection of Bcl-2.
품질
routinely evaluated by immunoblot on Raji RIPA cell lysate
표적 설명
26kDa
결합
Replaces: 04-436; OP60-100UG
물리적 형태
0.1M Tris-glycine, pH 7.4, 0.15M NaCl, 0.05% sodium azide before the addition of glycerol to 30%
Format: Purified
Protein G Purified
저장 및 안정성
2 years at -20°C
법적 정보
UPSTATE is a registered trademark of Merck KGaA, Darmstadt, Germany
면책조항
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
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Storage Class Code
12 - Non Combustible Liquids
WGK
WGK 2
Flash Point (°F)
Not applicable
Flash Point (°C)
Not applicable
시험 성적서(COA)
제품의 로트/배치 번호를 입력하여 시험 성적서(COA)을 검색하십시오. 로트 및 배치 번호는 제품 라벨에 있는 ‘로트’ 또는 ‘배치’라는 용어 뒤에서 찾을 수 있습니다.
Ekaterina Kim et al.
Leukemia, 34(6), 1588-1598 (2019-12-22)
Despite major improvements in treatment outcome with novel targeted therapies, such as the Bruton tyrosine kinase (BTK) inhibitor ibrutinib, chronic lymphocytic leukemia (CLL) remains incurable in the majority of patients. Activation of PI3K, NF-κB, and/or MYC has been linked to
S Krajewski et al.
Cancer research, 53(19), 4701-4714 (1993-10-01)
A multidisciplinary approach was taken to investigate the intracellular locations of the 26-kDa integral membrane protein encoded by the bcl-2 gene. Subcellular fractionation analysis of a t(14;18)-containing lymphoma cell line revealed the presence of Bcl-2 protein in nuclear, heavy-membrane, and
Programmed cell death: apoptosis and oncogenesis.
Williams, G T
Cell, 65, 1097-1098 (1991)
Maria Elena Mantione et al.
Cell death & disease, 15(3), 224-224 (2024-03-18)
Microenvironmental signals strongly influence chronic lymphocytic leukemia (CLL) cells through the activation of distinct membrane receptors, such as B-cell receptors, and inflammatory receptors, such as Toll-like receptors (TLRs). Inflammatory pathways downstream of these receptors lead to NF-κB activation, thus protecting
Maria Elena Mantione et al.
Frontiers in oncology, 12, 894413-894413 (2022-07-12)
Renal cell carcinoma is highly inflamed, and tumor cells are embedded into a microenvironment enriched with IL1. While inflammatory pathways are well characterized in the immune system, less is known about these same pathways in epithelial cells; it is unclear
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