SAB2500745
Anti-PAM/PAL antibody produced in goat
affinity isolated antibody, buffered aqueous solution
동의어(들):
Anti-PAL, Anti-PHM, Anti-Pancreatic peptidylglycine α-amidating monooxygenase, Anti-Peptidyl α-amidating enzyme, Anti-Peptidylglycine α-amidating monooxygenase
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모든 사진(1)
About This Item
추천 제품
일반 설명
Peptidylglycine α-amidating monooxygenase (PAM) is expressed in endocrine cells and neurons. It consists of two enzyme activities- peptidyl-glycine α-hydroxylating monoxygenase (PHM) and peptidyl-α-hydroxyglycine amidating lyase (PAL). The PAM gene is localized on human chromosome 5q21.1.
면역원
Peptide with sequence C-DQEKEDDGSESEE from the C Terminus of the protein sequence according to NP_000910.2; NP_620121.1; NP_620176.1; NP_620177.1.
생화학적/생리학적 작용
Peptidylglycine α-amidating monooxygenase (PAM) has a role in the biosynthesis of bioactive peptides. It is involved in C-terminal α-amidation, which influences the activity of regulatory peptides of the respiratory tract.
특징 및 장점
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물리적 형태
Supplied at 0.5 mg/mL in Tris saline with 0.02% sodium azide and 0.5% bovine serum albumin.
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신호어
Warning
유해 및 위험 성명서
예방조치 성명서
Hazard Classifications
Eye Irrit. 2 - Skin Irrit. 2
Storage Class Code
10 - Combustible liquids
WGK
WGK 2
Flash Point (°F)
Not applicable
Flash Point (°C)
Not applicable
시험 성적서(COA)
제품의 로트/배치 번호를 입력하여 시험 성적서(COA)을 검색하십시오. 로트 및 배치 번호는 제품 라벨에 있는 ‘로트’ 또는 ‘배치’라는 용어 뒤에서 찾을 수 있습니다.
The endocytic pathways of a secretory granule membrane protein in HEK293 cells: PAM and EGF traverse a dynamic multivesicular body network together.
Back N, et al.
European Journal of Cell Biology, 96(5), 407-417 (2017)
Peptidylglycine alpha-amidating monooxygenase: a multifunctional protein with catalytic, processing, and routing domains.
Eipper BA, et al.
Protein Science, 2(4), 489-497 (1993)
Distribution of peptidyl-glycine alpha-amidating mono-oxygenase (PAM) enzymes in normal human lung and in lung epithelial tumors.
Saldise L, et al.
The Journal of Histochemistry and Cytochemistry, 44(1), 3-12 (1996)
Localization of the gene encoding peptidylglycine alpha-amidating monooxygenase (PAM) to human chromosome 5q14-5q21.
Ouafik LH, et al.
Genomics, 18(2), 319-321 (1993)
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