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Merck
모든 사진(1)

문서

SAB2500444

Sigma-Aldrich

Anti-GAD2/GAD65 antibody produced in goat

affinity isolated antibody, buffered aqueous solution

동의어(들):

Anti-GAD65, Anti-Glutamate decarboxylase 2

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About This Item

MDL number:
UNSPSC 코드:
12352203
NACRES:
NA.41

생물학적 소스

goat

결합

unconjugated

항체 형태

affinity isolated antibody

항체 생산 유형

primary antibodies

클론

polyclonal

형태

buffered aqueous solution

종 반응성

human, mouse, chimpanzee, rat, canine

기술

indirect ELISA: suitable
western blot: suitable

UniProt 수납 번호

배송 상태

dry ice

저장 온도

−20°C

타겟 번역 후 변형

unmodified

유전자 정보

human ... GAD2(2572)

일반 설명

Glutamate decarboxylase 2 (GAD2) is a 65kDa protein expressed in β-cells. The gene encoding this protein is localized on human chromosome 10p12.1.

면역원

Peptide with sequence C-TLEDNEERMSRLSK from the internal region of the protein sequence according to NP_000809.1.

생화학적/생리학적 작용

Glutamate decarboxylase 2 (GAD2) is an isoform of glutamate decarboxylase, which is involved in the synthesis of γ-aminobutyric acid (GABA). GAD2 is an auto-antigen in type I diabetes and has been shown to have a role in gastric cancer.

특징 및 장점

Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.

물리적 형태

Supplied at 0.5 mg/mL in Tris saline with 0.02% sodium azide and 0.5% bovine serum albumin.

면책조항

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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픽토그램

Exclamation mark

신호어

Warning

유해 및 위험 성명서

예방조치 성명서

Hazard Classifications

Eye Irrit. 2 - Skin Irrit. 2

Storage Class Code

10 - Combustible liquids

WGK

WGK 2

Flash Point (°F)

Not applicable

Flash Point (°C)

Not applicable


시험 성적서(COA)

제품의 로트/배치 번호를 입력하여 시험 성적서(COA)을 검색하십시오. 로트 및 배치 번호는 제품 라벨에 있는 ‘로트’ 또는 ‘배치’라는 용어 뒤에서 찾을 수 있습니다.

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문서 라이브러리에서 최근에 구매한 제품에 대한 문서를 찾아보세요.

문서 라이브러리 방문

Plasma GAD65, a Marker for Early ?-Cell Loss After Intraportal Islet Cell Transplantation in Diabetic Patients.
Ling Z
The Journal of Clinical Endocrinology and Metabolism (2015)
Immuno-chemistry of hydroxyl radical modified GAD-65: A possible role in experimental and human diabetes mellitus.
Moinuddin
IUBMB Life, 67(10) (2015)
The role of glutamate decarboxylase 65 in gastric cancer development, progression, and prognosis.
Song Y
Histopathology (2013)
Epigenetic signature of panic disorder: A role of glutamate decarboxylase 1 (GAD1) DNA hypomethylation?
Katharina D
Progress in Neuro-Psychopharmacology & Biological Psychiatry (2013)

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