S5816
Stromal Cell-Derived Factor 1α/pre-B Cell Growth Stimulating Factor from mouse
>97% (SDS-PAGE), recombinant, expressed in E. coli, powder, suitable for cell culture
동의어(들):
SDF-1α/PBSF
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크기 선택
10 μG
₩651,732
₩651,732
구입 가능 여부는 고객센터에 문의하십시오.
기존과 동일한 품질을 인하된 가격으로 - 어려운 예산 상황을 머크와 함께 극복하세요
모든 사진(1)
크기 선택
보기 변경
10 μG
₩651,732
About This Item
₩651,732
구입 가능 여부는 고객센터에 문의하십시오.
기존과 동일한 품질을 인하된 가격으로 - 어려운 예산 상황을 머크와 함께 극복하세요
추천 제품
제품명
Stromal Cell-Derived Factor 1α/pre-B Cell Growth Stimulating Factor from mouse, SDF-1α, recombinant, expressed in E. coli, powder, suitable for cell culture
생물학적 소스
mouse
Quality Level
재조합
expressed in E. coli
분석
>97% (SDS-PAGE)
양식
powder
효능
0.15-0.6 ng/mL ED50
품질
endotoxin tested
분자량
predicted mol wt ~8 kDa
포장
pkg of 10 μg
저장 조건
avoid repeated freeze/thaw cycles
기술
cell culture | mammalian: suitable
불순물
<1 EU/μgtested (LAL test)
UniProt 수납 번호
저장 온도
−20°C
유전자 정보
mouse ... Cxcl12(20315)
일반 설명
Stromal derived factor-1 (SDF-1) is localized to adipocytes.[1]
애플리케이션
생화학적/생리학적 작용
SDF-1α/PBSF, a member of the α (CXC) chemokine family, is a chemoattractant for T lymphocytes and monocytes, but not neutrophils. SDF-1α/PBSF is highly conserved between species, with only one amino acid substitution between the human and mouse proteins. SDF-1α and SDF-1β (together also known as SDF-1α/PBSF) are encoded by a single gene and arise by alternative splicing. The two proteins are identical except for the four amino acid residues that are present in the C-terminal of SDF-1β and absent from SDF-1α..
Stromal derived factor-1 (SDF-1) is an insulin-desensitizing factor, upregulated during both starvation and obesity. Exogenic SDF-1 reduces insulin-mediated signaling and glucose uptake.[1] SDF-1 mediates migration of cortical interneurons and endothelial progenitor cells of the bone marrow through chemotaxis.[4][5]
물리적 형태
Lyophilized from a 0.2 μm filtered solution in 30% acetonitrile and 0.1% trifluoroacetic acid containing 0.5 mg bovine serum albumin.
제조 메모
Recombinant Mouse Stromal Cell-Derived Factor 1α (SDF-1α)/Pre-B Cell Growth Stimulating Factor (PBSF) is produced from a DNA sequence encoding the mature mouse SDF-1α protein sequence (amino acid residues 22-89) expressed in Escherichia coli. Recombinant mouse SDF-1α (68 amino acids) has a predicted molecular mass of approximately 8 kDa.
분석 메모
The biological activity is measured by its ability to chemoattract cultured human lymphocytes and mouse BaF3 cells transfected with human CXCR4.
Storage Class Code
11 - Combustible Solids
WGK
WGK 3
Flash Point (°F)
Not applicable
Flash Point (°C)
Not applicable
개인 보호 장비
Eyeshields, Gloves, type N95 (US)
SDF-1 Is an Autocrine Insulin-Desensitizing Factor in Adipocytes.
Shin J, et al.
Diabetes, 67(6), 1068-1078 (2018)
CXCR4 receptor positive spheroid forming cells are responsible for tumor invasion in vitro
Krohn A, et al.
Cancer Letters, 280, 65-71 (2009)
The Cytokine CXCL12 Promotes Basket Interneuron Inhibitory Synapses in the Medial Prefrontal Cortex.
Wu PR, et al.
Cerebral Cortex, 27(9), 4303-4313 (2017)
Mobilization of mesenchymal stem cells by stromal cell-derived factor-1 released from chitosan/tripolyphosphate/fucoidan nanoparticles
Huang YC, et al.
Acta Biomaterialia, 8, 1048-1056 (2012)
Yoshitsugu Takabatake et al.
Journal of the American Society of Nephrology : JASN, 20(8), 1714-1723 (2009-05-16)
CXC chemokine ligand 12 (CXCL12; stromal cell-derived factor 1) is a unique homeostatic chemokine that signals through its cognate receptor, CXCR4. CXCL12/CXCR4 signaling is essential for the formation of blood vessels in the gastrointestinal tract during development, but its contribution
활성 필터
자사의 과학자팀은 생명 과학, 재료 과학, 화학 합성, 크로마토그래피, 분석 및 기타 많은 영역을 포함한 모든 과학 분야에 경험이 있습니다..
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