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Merck
모든 사진(2)

주요 문서

S4026

Sigma-Aldrich

Semustine

동의어(들):

N-(2-Chloroethyl)-N′-(4-methylcyclohexyl)-N-nitrosourea, Methyl-CCNU

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크기 선택

100 MG
₩216,703

₩216,703


구입 가능 여부는 고객센터에 문의하십시오.

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보기 변경
100 MG
₩216,703

About This Item

실험식(Hill 표기법):
C10H18ClN3O2
CAS Number:
Molecular Weight:
247.72
MDL number:
UNSPSC 코드:
12352100
PubChem Substance ID:
NACRES:
NA.22

₩216,703


구입 가능 여부는 고객센터에 문의하십시오.

벌크 견적 요청

SMILES string

CC1CCC(CC1)NC(=O)N(CCCl)N=O

InChI

1S/C10H18ClN3O2/c1-8-2-4-9(5-3-8)12-10(15)14(13-16)7-6-11/h8-9H,2-7H2,1H3,(H,12,15)

InChI key

FVLVBPDQNARYJU-UHFFFAOYSA-N

애플리케이션

Commonly used in pharmacological studies involving:
  • Nutrient-sensitized screening for drugs that shift the energy metabolism from mitchondrial respiration to glycolysis
  • CEOP regimen with semustine used as induction chemotherapy in patients with lymphoma
  • Investigations into its use for chemotherapy

픽토그램

Skull and crossbonesHealth hazard

신호어

Danger

Hazard Classifications

Acute Tox. 2 Oral - Acute Tox. 3 Dermal - Acute Tox. 3 Inhalation - Carc. 1B - Eye Irrit. 2 - Repr. 1B - Skin Irrit. 2 - STOT SE 3

표적 기관

Respiratory system

Storage Class Code

6.1A - Combustible acute toxic Cat. 1 and 2 / very toxic hazardous materials

WGK

WGK 3

Flash Point (°F)

Not applicable

Flash Point (°C)

Not applicable

개인 보호 장비

Eyeshields, Faceshields, Gloves, type P3 (EN 143) respirator cartridges


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문서 라이브러리 방문

Qiu-bai Li et al.
Acta pharmacologica Sinica, 30(10), 1471-1478 (2009-09-22)
To analyze the results of idarubicin (IDA)- versus etoposide (VP16)-intensified myeloablative conditioning regimen in allogeneic hematopoietic stem cell transplantation (allo-SCT) for high-risk acute leukemia. From January 2005 to June 2008, 48 consecutive patients (male: n=29; median age: 30 years, range
Eleana Ntatsaki et al.
Rheumatology (Oxford, England), 50(6), 1019-1024 (2011-02-05)
The ANCA-associated vasculitides (AAVs) are conventionally treated with a strategy of remission induction followed by maintenance therapy using glucocorticoids combined with CYC during induction and AZA for maintenance. Recently, several randomized controlled trials have been published that question whether these
Xuejun Ma et al.
Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology, 93(3), 492-497 (2009-09-29)
In this randomized phase II study, we evaluated the efficacy of semustine added to CEOP regimen as induction chemotherapy in patients with stage I(E)/II(E) extranodal NK/T-cell lymphoma, nasal type in the upper aerodigestive tract. Seventy-five eligible patients were randomized to
[Advances in research on capecitabine as adjuvant treatment for colon cancer after radical resection].
Su-Zhan Zhang
Zhonghua zhong liu za zhi [Chinese journal of oncology], 32(11), 801-803 (2011-01-13)
1-(2-Chloroethyl)-3-(4-methylcyclohexyl)-1-nitrosourea.
Report on carcinogens : carcinogen profiles, 11, III53-III53 (2004-01-01)

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