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Merck
모든 사진(3)

문서

S3147

Sigma-Aldrich

5-Sulfosalicylic acid dihydrate

suitable for electrophoresis, ≥99%

동의어(들):

2-Hydroxy-5-sulfobenzoic acid

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About This Item

Linear Formula:
HO3SC6H3-2-(OH)CO2H·2H2O
CAS Number:
Molecular Weight:
254.21
Beilstein:
650741
EC Number:
MDL number:
UNSPSC 코드:
41105319
PubChem Substance ID:
NACRES:
NB.22

Quality Level

분석

≥99%

형태

powder or crystals

기술

electrophoresis: suitable

불순물

≤0.02% Insoluble matter
≤0.05% Salicylic Acid

mp

105-110 °C (lit.)

solubility

water: soluble 100 mg/mL, clear, colorless

음이온 미량물

chloride (Cl-): ≤0.001%
sulfate (SO42-): ≤0.035%

양이온 미량물

Fe: ≤0.001%
heavy metals (as Pb): ≤0.002%

SMILES string

[H]O[H].[H]O[H].OC(=O)c1cc(ccc1O)S(O)(=O)=O

InChI

1S/C7H6O6S.2H2O/c8-6-2-1-4(14(11,12)13)3-5(6)7(9)10;;/h1-3,8H,(H,9,10)(H,11,12,13);2*1H2

InChI key

BHDKTFQBRFWJKR-UHFFFAOYSA-N

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일반 설명

5-Sulfosalicylic acid is a strong acid capable of protonating water. It forms a new theophylline complex, which was investigated by X-ray photoelectron spectroscopy (XPS). It forms 1:1 proton-transfer compounds with the ortho-substituted monocyclic heteroaromatic Lewis bases. Their crystal structures have been studied.

애플리케이션

5-Sulfosalicylic acid (3.5%) in 12% trichloroacetic acid is commonly used as a fixing solution for proteins in agarose and polyacrylamide gels.
5-Sulfosalicylic acid dihydrate may be employed for the quantification of doxorubicin derived from PEGylated liposomal doxorubicin (Doxil) and its major metabolite in human plasma by HPLC. It may be used in the preparation of poly[[tris(di-2-pyridylamine)tris([μ]-5-sulfonatosalicylato)tricopper(II)] trihydrate].

분석 메모

Tested for use in fixing solutions for PAGE, SDS-PAGE and IEF.

픽토그램

Corrosion

신호어

Danger

유해 및 위험 성명서

Hazard Classifications

Eye Dam. 1 - Skin Corr. 1B

Storage Class Code

8A - Combustible corrosive hazardous materials

WGK

WGK 1

Flash Point (°F)

Not applicable

Flash Point (°C)

Not applicable

개인 보호 장비

dust mask type N95 (US), Eyeshields, Gloves


시험 성적서(COA)

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문서 라이브러리 방문

David L Chin et al.
Journal of chromatography. B, Analytical technologies in the biomedical and life sciences, 779(2), 259-269 (2002-10-04)
A high-performance liquid chromatographic method was developed for the quantification of doxorubicin derived from PEGylated liposomal doxorubicin (Doxil) and its major metabolite in human plasma. This method utilizes Triton X-100 to disperse the liposome, followed by a protein precipitation step
Hui Wang et al.
Frontiers in physiology, 11, 655-655 (2020-07-01)
Serotonin (5-HT), a monoaminergic neurotransmitter, involves in the regulation of many physiological functions. In the present study, the effects of 5-hydroxytryptophan (5-HTP), the precursor of 5-HT, on lipid metabolism and intestinal immune function in broiler chickens were investigated in chickens.
Joanna S Stevens et al.
The journal of physical chemistry. B, 114(44), 13961-13969 (2010-10-22)
Recent studies suggested that X-ray photoelectron spectroscopy (XPS) sensitively determines the protonation state of nitrogen functional groups in the solid state, providing a means for distinguishing between co-crystals and salts of organic compounds. Here we describe how a new theophylline
Megan A Dickson et al.
Reproductive biology and endocrinology : RB&E, 18(1), 49-49 (2020-05-16)
Cigarette smokers have a reduced risk of developing preeclampsia, possibly attributed to an increase in carbon monoxide (CO) levels. Carbon monoxide is a gasotransmitter that has been implicated in maintaining vascular tone, increasing angiogenesis, and reducing inflammation and apoptosis at
Hydrogen bonding in proton-transfer compounds of 5-sulfosalicylic acid with ortho-substituted monocyclic heteroaromatic Lewis bases.
Smith G, et al.
Journal of Chemical Crystallography, 36(12), 841-849 (2006)

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