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애플리케이션
Streptokinase (SK) is commonly used as a thrombolytic agent in the therapy of ischemic stroke. This therapy carries the important risk of intracerebral hemorrhage. Streptokinase is also used in the treatment of complicated parapneumonic effusions and empyema where adverse reactions, allergic type, are rare. The product has been used to measure SK activity in brain heart infusion culture supernatant fluids of the various wild-type and mutant strains of Streptococcus dysgalactiae subsp. Equisimilis.[1]
생화학적/생리학적 작용
Streptokinase C is an extracellular enzyme that is produced by various strains of β-hemolytic streptococci. It is a single-chain polypeptide that exerts its fibrinolytic action indirectly by activating the circulatory plasminogen.
단위 정의
One unit will liquify a standard clot of fibrinogen, plasminogen, and thrombin at pH 7.5 at 37 °C in 10 min.
물리적 형태
Supplied as a frozen solution containing 60 mM phosphate buffer and 0.6 M glutamate. Albumin-free
Storage Class Code
10 - Combustible liquids
WGK
WGK 3
Flash Point (°F)
Not applicable
Flash Point (°C)
Not applicable
가장 최신 버전 중 하나를 선택하세요:
Kerstin Steiner et al.
Infection and immunity, 70(7), 3627-3636 (2002-06-18)
Synthesis of the plasminogen activator streptokinase (SK) by group A streptococci (GAS) has recently been shown to be subject to control by two two-component regulators, covRS (or csrRS) and fasBCA. In independent studies, response regulator CovR proved to act as
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