This product is lyophilized from a solution containing sodium glutamate and human serum albumin. The material may be reconstituted in water. For assay purposes, this material is reconstituted in 10 mM Tris-HCl / 0.1 M NaCl / 0.1% BSA, pH 7.4 . The solution stability has not been determined.
S3134
Streptokinase from β-hemolytic Streptococcus (Lancefield Group C)
lyophilized powder, ≥2,000 units/mg solid
동의어(들):
Streptokinase from Streptococcus hemolyticus
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10000 UNITS
₩108,808
50000 UNITS
₩364,487
250000 UNITS
₩1,324,169
₩108,808
출고 가능일2025년 3월 31일세부사항
모든 사진(2)
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보기 변경
10000 UNITS
₩108,808
50000 UNITS
₩364,487
250000 UNITS
₩1,324,169
About This Item
₩108,808
출고 가능일2025년 3월 31일세부사항
추천 제품
양식
lyophilized powder
특이 활성도
≥2,000 units/mg solid
배송 상태
wet ice
저장 온도
−20°C
SMILES string
N1C(CC(C1)C2CCCCC2)C(=O)O
InChI
1S/C11H19NO2/c13-11(14)10-6-9(7-12-10)8-4-2-1-3-5-8/h8-10,12H,1-7H2,(H,13,14)
InChI key
XRZWVSXEDRYQGC-UHFFFAOYSA-N
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일반 설명
Research area: Cell signaling
Streptokinase is an extracellular enzyme produced by β-hemolytic Streptococcus. It is a single-chain polypeptide enzyme that consists of multiple structural domains, including α-, β-, and γ-domains.[1]
Streptokinase is an extracellular enzyme produced by β-hemolytic Streptococcus. It is a single-chain polypeptide enzyme that consists of multiple structural domains, including α-, β-, and γ-domains.[1]
애플리케이션
Streptokinase has been used in a study to compare primary coronary intervention and thrombolytic therapy in myocardial infarction patients. [2]
Streptokinase is commonly used as a thrombolytic agent in the therapy of ischemic stroke. This therapy carries the important risk of intracerebral hemorrhage. Streptokinase is also used in the treatment of complicated parapneumonic effusions and empyema where adverse reactions, allergic type, are rare.
생화학적/생리학적 작용
Streptokinase is a potent plasminogen activator. Unlike human proteins tissue plasminogen activator (tPA) and urokinase plasminogen activator (uPA), microbial streptokinase does not directly activate plasminogen. Instead, it activates plasminogen by fibrin-dependent and fibrin-independent. mechanisms.[1] Streptokinase is effective in thrombolytic therapy.[1] While streptokinase offers promising potential in treating ischemic stroke, its use also presents a significant risk of intracerebral hemorrhage. Streptokinase is also used in treating complicated parapneumonic effusions and empyema where allergic reactions, are rare.[3]
단위 정의
One unit is equal to the amount of activity in one unit from a Streptokinase International Standard reference vial.
물리적 형태
Lyophilized powder containing ~50% total protein by biuret and sodium glutamate. Total protein composed of enzyme protein and human serum albumin.
Storage Class Code
11 - Combustible Solids
WGK
WGK 3
Flash Point (°F)
Not applicable
Flash Point (°C)
Not applicable
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시험 성적서(COA)
Lot/Batch Number
이미 열람한 고객
Staphylokinase, a fibrin-specific plasminogen activator with therapeutic potential?
D Collen et al.
Blood, 84(3), 680-686 (1994-08-01)
Streptokinase--a clinically useful thrombolytic agent
Banerjee A, et al.
Biotechnology Advances, 22(4), 287-307 (2004)
Streptokinase--a clinically useful thrombolytic agent
Banerjee A, et al.
Biotechnology Advances, 22(4), 2004-2004 (2004)
Role of streptokinase in the treatment of acute loculated parapneumonic pleural effusions and empyema
Bouros D, et al.
Thorax, 49(9), 852-855 (1994)
Effects of plasminogen and streptokinase on the vital functions of nervous tissue cells in culture
Nikandrov, V., et al.
Biomeditsinskaia Khimiia, 54, 192-200 (2012)
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