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추천 제품
종 반응성
human
기술
ELISA: suitable
assay range
inter-assay cv: <10%
intra-assay cv: <12%
배송 상태
wet ice
저장 온도
−20°C
유전자 정보
human ... JAK2(3717)
일반 설명
The antibody pair provided in this kit recognizes Human Tyrosine-Phosphorylated-JAK2. The JAK2 (Janus kinase 2) gene is mapped to human chromosome 9p24.1.[1]
애플리케이션
For research use only. Not for use in diagnostic procedures.
Please refer to the attached General ELISA KIT Procedure (sandwich, competitive & Indirect ELISA)
Please refer to the attached General ELISA KIT Procedure (sandwich, competitive & Indirect ELISA)
생화학적/생리학적 작용
Janus kinase 2 (JAK2) mediates epithelial-mesenchymal transition in hepatocellular carcinoma.[2] The JAK2/STAT3 signaling pathway is associated with tumor development in a number of cancer such as gastric cancer.[3] Mutation in the JAK2 gene is known to activate JAK2 receptor action even in the absence of ligand, inducing cell proliferation and opposing apoptosis.[4]
신호어
Warning
유해 및 위험 성명서
예방조치 성명서
Hazard Classifications
Met. Corr. 1
Storage Class Code
8A - Combustible corrosive hazardous materials
Flash Point (°F)
Not applicable
Flash Point (°C)
Not applicable
가장 최신 버전 중 하나를 선택하세요:
CD 274 (PDL 1) and JAK 2 genomic amplifications in pulmonary squamous?cell and adenocarcinoma patients.
Clave S, et al.
Histopathology, 72(2), 259-269 (2018)
SIRT6 inhibits growth of gastric cancer by inhibiting JAK2/STAT3 pathway.
Zhou J, et al.
Oncology Reports, 38(2), 1059-1066 (2017)
The genetic basis of haematological cancers (2016)
Norcantharidin inhibits IL-6-induced epithelial?mesenchymal transition via the JAK2/STAT3/TWIST signaling pathway in hepatocellular carcinoma cells.
Gao Y, et al.
Oncology Reports, 38(2), 1224-1232 (2017)
활성 필터
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고객지원팀으로 연락바랍니다.