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Merck
모든 사진(1)

주요 문서

RAB0386

Sigma-Aldrich

Brain Natriuretic Peptide EIA Kit

for serum, plasma, culture supernatant and cell lysates

동의어(들):

Gamma-brain natriuretic peptide, Natriuretic peptides B , BNP

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About This Item

UNSPSC 코드:
41123300
NACRES:
NA.32
가격 및 재고 정보를 현재 이용할 수 없음 고객지원팀으로 연락바랍니다.

종 반응성

human, mouse, rat

포장

kit of 96 wells (12 strips x 8 wells)

기술

ELISA: suitable
enzyme immunoassay: suitable

입력

sample type serum
sample type culture supernatant(s)
sample type plasma
sample type cell lysate

assay range

inter-assay cv: <15%
intra-assay cv: <10%
sensitivity: 1.66 pg/mL
standard curve range: 0.1–1000 pg/mL

검출 방법

colorimetric

배송 상태

wet ice

저장 온도

−20°C

유전자 정보

human ... NPPB(4879)

일반 설명

The BNP Enzyme Immunoassay (EIA) Kit is an in vitro quantitative assay for detecting BNP peptide based on the principle of Competitive Enzyme Immunoassay.

면역원

Brain Natriuretic Peptide, synthetic peptide

애플리케이션

For research use only. Not for use in diagnostic procedures.
Brain natriuretic peptide EIA Kit has been used to measure brain natriuretic peptide (BNP) secreted in human neonatal ventricular cardiomyocyte culture.[1][2]

생화학적/생리학적 작용

Brain natriuretic peptide (BNP) expressed in mammalian brain and atrial natriuretic peptide (ANP) facilitates various physiological functions including regulation of blood pressure and cardiac remodeling.[3] BNP acts as a potential biomarker of high left ventricular end-diastolic pressure in patients with symptomatic left ventricular (LV) dysfunction.[4] Elevated expression of BNP is observed in acute myocardial infarction (AMI) patients. BNP is also implicated in several biological functions such as diuresis, natriureis, hypotensive action and inhibition of aldosterone secretion.[3]

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제품 번호
설명
SDS

픽토그램

Corrosion

신호어

Warning

유해 및 위험 성명서

예방조치 성명서

Hazard Classifications

Met. Corr. 1

Storage Class Code

8A - Combustible corrosive hazardous materials

Flash Point (°F)

Not applicable

Flash Point (°C)

Not applicable


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시험 성적서(COA)

Lot/Batch Number

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문서 라이브러리에서 최근에 구매한 제품에 대한 문서를 찾아보세요.

문서 라이브러리 방문

A new natriuretic peptide in porcine brain.
Sudoh T
Nature, 332(6159), 78-81 (1988)
Csaba Matyas et al.
Hepatology (Baltimore, Md.), 71(4), 1391-1407 (2019-08-31)
Hepatic cardiomyopathy, a special type of heart failure, develops in up to 50% of patients with cirrhosis and is a major determinant of survival. However, there is no reliable model of hepatic cardiomyopathy in mice. We aimed to characterize the
Cara Tomas et al.
Open heart, 4(2), e000697-e000697 (2018-01-19)
To explore levels of the brain natriuretic peptide (BNP) and how these associate with the cardiac abnormalities recently identified in chronic fatigue syndrome (CFS). Cardiac magnetic resonance examinations were performed using 3T Philips Intera Achieva scanner (Best, Netherlands) in CFS
Azar Hosseini et al.
Frontiers in pharmacology, 13, 909079-909079 (2022-06-28)
Background: Doxorubicin as an anti-cancer drug causes cardiotoxicity, limiting its tolerability and use. The mechanism of toxicity is due to free radical production and cardiomyocytes injury. This research evaluated Rheum turkestanicum (R.turkestanicum) extract against doxorubicin cardiotoxicity due to its considerable
Héctor Fernández-Susavila et al.
Journal of the American Heart Association, 6(12) (2017-12-06)
Besides the relevant role of brain-type natriuretic peptide (BNP) as biomarker of cardioembolic strokes, new experimental evidences suggest that this peptide may mediate neuroprotective effects. In this study, we have evaluated for the first time the clinical association between BNP

질문

  1. What is the stability of the anti-BNP antibody concentrate (item N reconstituted with 55 ul of 1X Assay Diluent) from RAB0386 when stored at 4C?

    1 답변
    1. Storing and reusing the reconstituted antibody item N is not recommended as it is not stable when stored. The kit includes 2 vials so that a partial plate may be run.

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