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NPPB

natriuretic peptide B

Synonyms:
BNP
Species:
UniProtKB ID:
Gene ID:
  • Human(4879) Summary: This gene is a member of the natriuretic peptide family and encodes a secreted protein which functions as a cardiac hormone. The protein undergoes two cleavage events, one within the cell and a second after secretion into the blood. The protein's biological actions include natriuresis, diuresis, vasorelaxation, inhibition of renin and aldosterone secretion, and a key role in cardiovascular homeostasis. A high concentration of this protein in the bloodstream is indicative of heart failure. Mutations in this gene have been associated with postmenopausal osteoporosis. [provided by RefSeq, Jul 2008]
  • Mouse(18158) natriuretic peptide type B
  • Rat(25105) natriuretic peptide B
  • domestic cat(493764) natriuretic peptide B
  • dog(487441) natriuretic peptide B
  • chicken(395765) natriuretic peptide B
  • naked mole-rat(101718083) natriuretic peptide B
  • sheep(100294642) natriuretic peptide B
  • cow(508734) natriuretic peptide B

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ELISA

Product Number
Description
Species
Human proNPPB / Natriuretic Peptides B ELISA Kit, for serum, plasma, cell culture supernatants and urine,
Species
human
Human NPPB / Natriuretic Peptides B ELISA Kit, for serum, plasma, cell culture supernatants and urine,
Species
human
Brain Natriuretic Peptide EIA Kit, for serum, plasma, culture supernatant and cell lysates,
Species
human

Antibodies

Product Number
Description
Species Reactivity
Application
Anti-Nppb Antibody Produced In Rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Species Reactivity
human
Application
immunofluorescence
Anti-NPPB antibody produced in rabbit, purified immunoglobulin, buffered aqueous solution,
Species Reactivity
human
Application
western blot
Monoclonal Anti-NPPB antibody produced in mouse, clone 2D11, purified immunoglobulin, buffered aqueous solution,
Species Reactivity
human
Application
ELISA
immunoprecipitation (IP)

western blot
Anti-human brain natriuretic peptide, clone 57, clone 57, from mouse,
Species Reactivity
human
Application
ELISA
western blot
Anti-human brain natriuretic peptide, clone 26, clone 26, from mouse,
Species Reactivity
human
Application
ELISA
western blot

Proteins

Product Number
Description
Species
Brain Natriuretic Peptide-32 human, ≥97% (HPLC), powder,
Species
human

esiRNA

Product Number
Description
Species
MISSION® esiRNA, targeting mouse Nppb,
Species
mouse