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Merck
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Q111

Sigma-Aldrich

(±)-Quinpirole dihydrochloride

powder

동의어(들):

trans-(±)-4,4a,5,6,7,8,8a,9-Octahydro-5-propyl-1H-pyrazolo[3,4-g]quinoline dihydrochloride, LY-141,865

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About This Item

실험식(Hill 표기법):
C13H21N3 · 2HCl
CAS Number:
73625-62-4
Molecular Weight:
292.25
MDL number:
MFCD01321054
UNSPSC 코드:
12352200
PubChem Substance ID:
24278670
NACRES:
NA.77
제품 Q111은(는)귀하의 국가에서 현재 판매되지 않습니다. 고객지원팀으로 연락바랍니다.

양식

powder

Quality Level

100

색상

white

solubility

H2O: 28 mg/mL

저장 온도

−20°C

SMILES string

Cl.Cl.[H][C@]12CCCN(CCC)[C@]1([H])Cc3cn[nH]c3C2

InChI

1S/C13H21N3.2ClH/c1-2-5-16-6-3-4-10-7-12-11(8-13(10)16)9-14-15-12;;/h9-10,13H,2-8H2,1H3,(H,14,15);2*1H/t10-,13-;;/m1../s1

InChI key

GJIGRGIGKHPYTK-OWVUFADGSA-N

유전자 정보

human ... DRD2(1813)

생화학적/생리학적 작용

D2-like dopamine receptor agonist that possesses some activity at D3 sites.

법적 정보

Manufactured and sold with the permission of Eli Lilly and Company.

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point (°F)

Not applicable

Flash Point (°C)

Not applicable

개인 보호 장비

Eyeshields, Gloves, type N95 (US)

가장 최신 버전 중 하나를 선택하세요:

시험 성적서(COA)

Lot/Batch Number
0000034129
013M4602V
022M4614V
088K4614
056K4623

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Sigma-Aldrich

A4393

R-(−)-Apomorphine hydrochloride hemihydrate

Cristina Cariulo et al.
Biochemical and biophysical research communications, 521(3), 549-554 (2019-11-05)
Huntington's disease (HD) is a progressive neurodegenerative disorder caused by an expansion of a CAG triplet repeat (encoding for a polyglutamine tract) within the first exon of the huntingtin gene. Expression of the mutant huntingtin (mHTT) protein can result in
D Eilam et al.
European journal of pharmacology, 161(2-3), 151-157 (1989-02-28)
The effects of the D-2 agonist quinpirole on forward progression, and on vertical and lateral movements, were measured for 2 h in rats injected with either saline, 0.03, 0.125, 0.5 or 8 mg/kg of the drug. Results showed that the
Gunnar F Kwakye et al.
Neurotoxicology, 70, 48-61 (2018-11-07)
Huntington's disease (HD) is functionally linked to environmental factors including cigarette use and dyshomeostasis in the levels of metals. Interestingly, one of the most abundant heavy metals in cigarettes is cadmium (Cd), which also accumulates in the striatum and causes
L J Munro et al.
Brain research, 746(1-2), 231-238 (1997-01-23)
Dopamine (DA) D2 and gamma-aminobutyric acid (GABA)A somatodendritic receptors tonically inhibit mesolimbic projection neurons in the A10 DA cell grouping of the ventral tegmentum. In the present study we determined the contribution of the ventral tegmental area (VTA) to the
S Rosenzweig-Lipson et al.
Pharmacology, biochemistry, and behavior, 51(4), 843-848 (1995-08-01)
The present study investigated whether potassium channel blockade could modify the behavioral effects of the dopamine D2/D3 receptor agonist quinpirole in squirrel monkeys. The duration of immobility and/or unusual postures indicative of catalepsy-associated behavior or the duration of scratching, known
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