PZ0177
OSU6162 hydrochloride
≥98% (HPLC)
동의어(들):
PNU-96391; PNU-0096391; OSU-6162; (S)-(-)-(3-methanesulfonyl-phenyl)-1-propyl-piperidine hydrochloride; (S,S)-3-[3-(Methylsulfonyl)phenyl]-1-propylpiperidine hydrochloride
로그인조직 및 계약 가격 보기
크기 선택
5 MG
₩173,362
25 MG
₩593,978
모든 사진(1)
크기 선택
보기 변경
5 MG
₩173,362
25 MG
₩593,978
About This Item
실험식(Hill 표기법):
C15H23NO2S·HCl
CAS Number:
Molecular Weight:
317.87
MDL number:
UNSPSC 코드:
51111800
PubChem Substance ID:
NACRES:
NA.77
추천 제품
분석
≥98% (HPLC)
양식
powder
광학 활성
[α]/D -5 to -7°, c = 1 in methanol
색상
white to tan
solubility
H2O: ≥16 mg/mL
저장 온도
−20°C
SMILES string
Cl.CCCN1CCC[C@H](C1)c2cccc(c2)S(C)(=O)=O
InChI
1S/C15H23NO2S.ClH/c1-3-9-16-10-5-7-14(12-16)13-6-4-8-15(11-13)19(2,17)18;/h4,6,8,11,14H,3,5,7,9-10,12H2,1-2H3;1H/t14-;/m1./s1
InChI key
LEMGVHZVBREXAD-PFEQFJNWSA-N
생화학적/생리학적 작용
OSU6162 (PNU-96391) is a dopamine stabilizer, a drug that can stimulate or inhibit dopaminergic signaling depending on the dopaminergic tone. Dopaminergic stabilizers have been proposed to act as partial dopamine receptor agonists or as antagonists with both dopamine and behavioral stabilizing activity. Although affinity is not high (in vitro binding affinity for dopamine D2 receptor has a Ki of 447 nM), OSU6162 shows a high level of receptor occupancy.
OSU6162 is a dopamine stabilizer
특징 및 장점
This compound is featured on the Dopamine Receptors page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.
법적 정보
Sold for research purposes under agreement from Pfizer Inc.
신호어
Warning
유해 및 위험 성명서
Hazard Classifications
Acute Tox. 4 Oral - Eye Irrit. 2
Storage Class Code
11 - Combustible Solids
WGK
WGK 3
Flash Point (°F)
Not applicable
Flash Point (°C)
Not applicable
가장 최신 버전 중 하나를 선택하세요:
시험 성적서(COA)
Lot/Batch Number
Nelleke Tolboom et al.
Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology, 40(2), 472-479 (2014-09-25)
(-)-OSU6162 is a dopamine stabilizer that can counteract both hyperdopaminergic and hypodopaminergic states. In this study, D2/D3 receptor occupancy of (-)-OSU6162 in the human brain was investigated using positron emission tomography (PET). Twelve male healthy volunteers underwent [(11)C]raclopride PET scanning
문서
We offer many products related to dopamine receptors for your research needs.
활성 필터
자사의 과학자팀은 생명 과학, 재료 과학, 화학 합성, 크로마토그래피, 분석 및 기타 많은 영역을 포함한 모든 과학 분야에 경험이 있습니다..
고객지원팀으로 연락바랍니다.
