₩618,643
예상 입고일2025년 8월 04일세부사항
기존과 동일한 품질을 인하된 가격으로 - 어려운 예산 상황을 머크와 함께 극복하세요
추천 제품
생물학적 소스
rabbit
결합
unconjugated
항체 형태
affinity isolated antibody
항체 생산 유형
primary antibodies
클론
polyclonal
양식
buffered aqueous solution
분자량
predicted mol wt 46 kDa
종 반응성
mouse, human, rat
기술
immunohistochemistry: suitable
indirect ELISA: suitable
western blot: suitable
UniProt 수납 번호
배송 상태
dry ice
저장 온도
−20°C
타겟 번역 후 변형
unmodified
유전자 정보
mouse ... Casp12(12364)
일반 설명
Caspase-12 (CASP12) is an immunomodulatory factor, that is present in the cytoplasmic side of the ER (endoplasmic reticulum). It is upregulated highly in muscle, liver and kidney.
면역원
a synthetic peptide corresponding to amino acids within the small cleavage product of murine caspase-12.
생화학적/생리학적 작용
Caspase-12 (CASP12) plays an important role in endoplasmic reticulum (ER)-related apoptosis. It moderates hepatocyte apoptosis prompted by carbon tetrachloride. Lack of caspase-12 (CASP12) increases cytokine responses.
결합
The action of this antibody can be blocked using blocking peptide SBP3197.
물리적 형태
Solution in phosphate buffered saline containing 0.02% sodium azide
면책조항
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
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관련 제품
Storage Class Code
10 - Combustible liquids
WGK
WGK 2
Flash Point (°F)
Not applicable
Flash Point (°C)
Not applicable
가장 최신 버전 중 하나를 선택하세요:
Caspase-12 deficiency enhances cytokine responses but does not protect against lethal Plasmodium yoelii 17XL infection
Miu J, et al.
Parasite Immunology, 32(11-12), 773-778 (2010)
Caspase-12 mediates carbon tetrachloride-induced hepatocyte apoptosis in mice
Liu H, et al.
World Journal of Gastroenterology, 20(48), 18189-18198 (2014)
The resveratrol attenuates ethanol-induced hepatocyte apoptosis via inhibiting ER-related caspase-12 activation and PDE activity in vitro
Liu LQ, et al.
Alcoholism, Clinical and Experimental Research, 38(3), 683-693 (2014)
Caspase-12, but Not Caspase-11, Inhibits Obesity and Insulin Resistance
Skeldon AM, et al.
Journal of Immunology, 196(1), 437-447 (2016)
Juan Carlos Gómora-García et al.
Cell death discovery, 7(1), 131-131 (2021-06-05)
Altered protein homeostasis is associated with neurodegenerative diseases and acute brain injury induced under energy depletion conditions such as ischemia. The accumulation of damaged or unfolded proteins triggers the unfolded protein response (UPR), which can act as a homeostatic response
활성 필터
자사의 과학자팀은 생명 과학, 재료 과학, 화학 합성, 크로마토그래피, 분석 및 기타 많은 영역을 포함한 모든 과학 분야에 경험이 있습니다..
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