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Merck
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P8920

Sigma-Aldrich

Poly-L-lysine solution

Poly-L-lysine solution
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0.1 % (w/v) in H2O

동의어(들):

2-(4-Cyanoanilino)-4,6-dichloropyrimidine, 4-[(4,6-Dichloro-2-pyrimidinyl)amino]benzonitrile

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크기 선택

100 ML
₩251,416
500 ML
₩973,690

₩251,416

예상 입고일2025년 1월 31일세부사항

벌크 견적 요청
모든 사진(1)

크기 선택

보기 변경
100 ML
₩251,416
500 ML
₩973,690

About This Item

CAS Number:
25988-63-0
MDL number:
MFCD00165424
UNSPSC 코드:
41116121
eCl@ss:
32160406
NACRES:
NA.47

₩251,416

예상 입고일2025년 1월 31일세부사항

벌크 견적 요청

생물학적 소스

synthetic

Quality Level

200

유통기한

Expiry date on the label.

분자량

150,000-300,000

농도

0.1 % (w/v) in H2O

색상

colorless

응용 분야

hematology
histology

저장 온도

room temp

SMILES string

N([C@@H](CCCCN)C(=O)N[C@@H](CCCCN)C(=O)O)C(=O)[C@@H](N)CCCCN

InChI

1S/C18H38N6O4/c19-10-4-1-7-13(22)16(25)23-14(8-2-5-11-20)17(26)24-15(18(27)28)9-3-6-12-21/h13-15H,1-12,19-22H2,(H,23,25)(H,24,26)(H,27,28)/t13-,14-,15-/m0/s1

InChI key

WBSCNDJQPKSPII-KKUMJFAQSA-N

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관련 카테고리

애플리케이션

Poly-L-lysine solution has been used for the attachment of endothelial cell cross sections to UV-crosslinked PET membrane frame slides.[1] Poly-L-lysine coated slides were used for the placement of tissue sections for immunohistochemical assay.[2]
Poly-L-lysine polymers can be used in promoting cell adhesion to solid substrates, conjugation to methotrexate for increased drug transport, microencapsulation of islets, cell microencapsulation technology, microarray glass slide coating, and chromosomal preparations. Lower molecular weight poly-L-lysine (30,000-70,000) is less viscuous in solution, but higher molecular weight versions provide more attachment sites per molecule.

생화학적/생리학적 작용

Poly-L-lysine is a nonspecific attachment factor for cells useful in promoting cell adhesion to solid substrates by enhancing electrostatic interaction between negatively charged ions of the cell membrane and the culture surface. When it is absorbed to the cell culture surface, poly-L-lysine functions to increase the number of positively charged sites available for cell binding. With cells that can digest poly-L-lysine, poly-D-lysine should be used as the attachment factor.

성분

Poly-L-lysine is a positively charged amino acid polymer with approximately one HBr per lysine residue. The hydrobromide allows the poly-L-lysine to be in a crystalline form soluble in water. A small amount of product may be found in the beta structure because the HBr interferes with hydrogen bonding between amino and either the carboxyl groups or N or O containing moieties.

제조 메모

This product is supplied as a 0.10% (w/v) solution in water. Coating slides with this solution should be followed with a 5 minute incubation and drying the slides at room temperature. Coated slides will be stable for one year if protected from dust.

교체됨

제품 번호
설명
가격

픽토그램

Exclamation markEnvironment
GHS07,GHS09

신호어

Warning

유해 및 위험 성명서

H315,H317,H319,H411

Hazard Classifications

Aquatic Chronic 2 - Eye Irrit. 2 - Skin Irrit. 2 - Skin Sens. 1

Storage Class Code

12 - Non Combustible Liquids

WGK

WGK 3

Flash Point (°F)

Not applicable

Flash Point (°C)

Not applicable

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시험 성적서(COA)

Lot/Batch Number
0000353387
0000309445
0000353387
0000309447
SLCP1100

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관련 콘텐츠

Hematology

치료 예방 및 혈액학 검사에 사용되는 염색과 염료를 포함하여 혈액, 혈액형성 기관 및 혈액 질환에 대해 알아보십시오.

Hematology

Learn about the clinical study of blood, blood-forming organs, and blood diseases including the treatment, prevention, and stains and dyes used in hematology testing.

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질문

1–4 / 4 질문  

  1. Hello! How many microscopy slides can I adhesive for every 100 milliliters of this solution( Poli-L- Lisine),? Gratitude!

    1 답변

    1. The number of slides that may be coated is dependent upon the surface area. The general use instructions recommend using 0.5 - 1.0 mL per 25 cm2 coating area - the 25 cm2 value is based on a T-25 tissue culture flask. A standard microscope slide has an approximate area of 1.3 cm2.

      Please see the link below to review the product datasheet which included a general protocol for coating: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/product/documents/784/704/p6407pis.pdf

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  2. Is Product P8920, Poly-L-lysine solution, recommended for cell culture use?

    1 답변

    1. No, the product contain 0.01% thimerosal as a preservative. For cell culture use, product P4832 is recommended.  This solution has the same molecular weight as P8920 but contains no preservative.  P4832 is sterile filtered and is considered suitable for cell culture use.

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  3. What is the Department of Transportation shipping information for this product?

    1 답변

    1. Transportation information can be found in Section 14 of the product's (M)SDS.To access the shipping information for this material, use the link on the product detail page for the product.

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  4. What are the recommended uses for Product P8920, Poly-L-lysine solution?

    1 답변

    1. P8920 was developed for use in coating slides intended for use in either histology or immunohistochemistry.  Poly-L-lysine is preferred for uses such as silver staining procedures that require an alkaline pH.  Silane coated slides may be more effective is a low pH is required.

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후기

1명의 제품 평가자(총 2명)가 샘플 제품을 받았거나 프로모션에 참여했습니다

활성 필터

  1. Des Plaines, Illinois
    • 상품평 1개
    • 투표 0개
    별 5개 중 5개입니다.

    stick with Poly-L-Lysine

    first purchased in 1993
    has been used regularly in our production ever since
    performs flawlessly

    Google로 번역

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  2. 1 평점-상품평만

자사의 과학자팀은 생명 과학, 재료 과학, 화학 합성, 크로마토그래피, 분석 및 기타 많은 영역을 포함한 모든 과학 분야에 경험이 있습니다..

고객지원팀으로 연락바랍니다.