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Merck
모든 사진(5)

문서

P2658

Sigma-Aldrich

Poly-L-lysine hydrochloride

suitable for cell culture, Mol wt 15,000-30,000

동의어(들):

L-Lysine hydrochloride homopolymer

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모든 사진(5)

About This Item

CAS Number:
26124-78-7
MDL number:
MFCD00081870
UNSPSC 코드:
12352209
eCl@ss:
32160406
NACRES:
NA.26

product name

Poly-L-lysine hydrochloride, mol wt 15,000-30,000

형태

powder or solid

Quality Level

200

분자량

15,000-30,000

기술

cell culture | mammalian: suitable

색상

white to light yellow

응용 분야

cell analysis

저장 온도

−20°C

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관련 카테고리

애플리케이션

Poly-L-lysine hydrochloride has been used to coat glass slides and coverslips to facilitate cell attachment.
Poly-lysine with mol. wt. >70,000 is useful in promoting cell adhesion to solid substrates.

생화학적/생리학적 작용

L-Lysine is believed to prevent osteoporosis of bones, which is a characteristics of vascular calcification. Glutaric aciduria type I and pyridoxine-dependent epilepsy occurs due to lack of L-lysine catabolic pathway. Lysine participates in the regulation of NO (nitric oxide) synthesis. It possesses antiviral activity, therefore it is used in the treatment of Herpes simplex. L-Lysine is associated with a number of biochemical reactions such as acetylation, O-linked glycosylation, ubiquitination and protein methylation. Poly-L-lysine is considered as a biocompatible polymer and serves for the purpose of drug delivery across cell membrane. It is useful as one of the nanosized contrast agents in MRI (magnetic resonance imaging).

분석 메모

Molecular weight based on viscosity.

기타 정보

For additional technical information on polyamino acids please visit the Polyamino acid FAQ resource.

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point (°F)

Not applicable

Flash Point (°C)

Not applicable

개인 보호 장비

Eyeshields, Gloves, type N95 (US)

시험 성적서(COA)

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문서 라이브러리 방문

The role of signaling pathways on proliferation and self-renewal of cultured bovine primitive germ cells
Sahare Mahesh
Reproductive medicine and biology, 14(1) (2015)
Primary culture of neural precursors from the ovine central nervous system (CNS)
A. H. Duitozz and T. Hevor
Journal of Neuroscience Methods, 131-140 (2001)
Multi-technique characterization of poly-L-lysine dendrigrafts-Cu(II) complexes for biocatalysis.
Rossi JC
Macromolecular Bioscience, 15(2), 275-290 (2015)
Archishman Ghosh et al.
Proceedings of the National Academy of Sciences of the United States of America, 116(39), 19474-19483 (2019-09-12)
Membraneless organelles, corresponding to the droplet phase upon liquid-liquid phase separation (LLPS) of protein or protein-RNA mixtures, mediate myriad cellular functions. Cells use a variety of biochemical signals such as expression level and posttranslational modification to regulate droplet formation and
Mahesh Sahare et al.
Reproduction, fertility, and development, 28(12), 2039-2050 (2015-07-17)
Spermatogonial stem cells (SSCs) are unipotent in nature, but mouse SSCs acquire pluripotency under the appropriate culture conditions. Although culture systems are available for rodent and human germ-cell lines, no proven culture system is yet available for livestock species. Here
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