추천 제품
양식
lyophilized powder
Quality Level
특이 활성도
≥20 units/mg protein
구성
Protein, 5-20% biuret
UniProt 수납 번호
저장 온도
−20°C
유전자 정보
cow ... PLA2G1B(282457)
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일반 설명
Phospholipase A2 from bovine pancreas is a calcium-dependent lipolytic enzyme.[1]
애플리케이션
생화학적/생리학적 작용
Hydrolyzes the β-ester bond of zwitterionic glycerophospholipids. Preferred substrates are phosphatidylcholine, phosphatidylethanolamine, and their plasmalogen analogues. Phosphatidylinositol and phosphatidylserine are also hydrolyzed. Aggressively attacks phospholipids in membranes of intact cells.
포장
Package size based on protein content
단위 정의
One unit will hydrolyze 1.0 μmole of soybean L-α-phosphatidylcholine to L-α-lysophosphatidylcholine and a fatty acid per min at pH 8.0 and 37 °C.
물리적 형태
Contains Tris buffer salts.
분석 메모
Protein determined by biuret.
저해제
제품 번호
설명
가격
Storage Class Code
11 - Combustible Solids
WGK
WGK 1
Flash Point (°F)
Not applicable
Flash Point (°C)
Not applicable
개인 보호 장비
Eyeshields, Gloves, type N95 (US)
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시험 성적서(COA)
Lot/Batch Number
이미 열람한 고객
Renal tubular triglyercide accumulation following endotoxic, toxic, and ischemic injury.
Zager RA
Kidney International, 67(1), 111-121 (2005)
Triglyceride accumulation in injured renal tubular cells: alterations in both synthetic and catabolic pathways.
Johnson AC
Kidney International, 67(6), 2196-2209 (2005)
Phospholipase A2 activity can protect renal tubules from oxygen deprivation injury.
Zager RA
Proceedings of the National Academy of Sciences of the USA, 90(17), 8297-8301 (1993)
Ming Chen et al.
Scientific reports, 7(1), 15931-15931 (2017-11-23)
Hepatitis C virus (HCV), dengue virus (DENV) and Japanese encephalitis virus (JEV) belong to the family Flaviviridae. Their viral particles have the envelope composed of viral proteins and a lipid bilayer acquired from budding through the endoplasmic reticulum (ER). The
K Sekar et al.
Acta crystallographica. Section D, Biological crystallography, 62(Pt 4), 392-397 (2006-03-23)
The lipolytic enzyme phospholipase A2 plays a crucial role in lipid metabolism and catalyzes hydrolysis of the fatty-acid ester bond at the sn-2 position of phospholipids. Here, the crystal structure (1.7 A resolution) of the triple mutant (K53,56,121M) of bovine
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