P8296
5-Phospho-D-ribose 1-diphosphate pentasodium salt
≥75% (HPLC)
동의어(들):
α-D-Ribosyl diphosphate 5-phosphate pentasodium salt, 5-Phospho-α-D-ribosyl diphosphate, 5-Phosphoribosyl 1-pyrophosphate pentasodium salt, P-Rib-PP, PRPP pentasodium salt
로그인조직 및 계약 가격 보기
크기 선택
25 MG
₩189,095
100 MG
₩452,589
250 MG
₩1,086,964
500 MG
₩1,349,138
모든 사진(4)
크기 선택
보기 변경
25 MG
₩189,095
100 MG
₩452,589
250 MG
₩1,086,964
500 MG
₩1,349,138
About This Item
실험식(Hill 표기법):
C5H8Na5O14P3
CAS Number:
Molecular Weight:
499.98
Beilstein:
6043637
MDL number:
UNSPSC 코드:
12352201
PubChem Substance ID:
NACRES:
NA.25
추천 제품
분석
≥75% (HPLC)
양식
powder
불순물
<18% water (Karl Fischer)
색상
white
solubility
water: 50 mg/mL, clear to slightly hazy, colorless to very faintly yellow
배송 상태
dry ice
저장 온도
−20°C
SMILES string
[Na+].[Na+].[Na+].[Na+].O[C@H]1[C@@H](O)[C@H](O[C@@H]1COP(O)([O-])=O)OP([O-])(=O)OP([O-])([O-])=O
InChI
1S/C5H13O14P3.4Na/c6-3-2(1-16-20(8,9)10)17-5(4(3)7)18-22(14,15)19-21(11,12)13;;;;/h2-7H,1H2,(H,14,15)(H2,8,9,10)(H2,11,12,13);;;;/q;4*+1/p-4/t2-,3-,4-,5?;;;;/m1..../s1
InChI key
QZAPPJHVNYCTAX-CKJQBBATSA-J
유사한 제품을 찾으십니까? 방문 제품 비교 안내
애플리케이션
Pentasodium salt has been used in a study to assess the relationship between the muscarinic receptor cationic current and internal calcium in guinea-pig jejunal smooth muscle cells. [1] It has also been used in a study to investigate inhibitors of the bacterial cell wall biosynthesis of the enzyme Mur D. [2]
기질
Substrate for phosphoribosyltransferases in the synthesis of nucleotides.
분석 메모
Purity ≥ 75% based on an assay system using orotidine-5′-phosphate pyrophosphorylase and orotidine-5′-phosphate decarboxylase mixed enzymes.
기타 정보
To gain a comprehensive understanding of our extensive range of Monosaccharides for your research, we encourage you to visit our Carbohydrates Category page.
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시험 성적서(COA)
Lot/Batch Number
이미 열람한 고객
L D Gegnas et al.
Bioorganic & medicinal chemistry letters, 8(13), 1643-1648 (1999-01-05)
A series of transition-state analog inhibitors of the D-glutamic acid-adding enzyme (MurD) of bacterial peptidoglycan biosynthesis has been synthesized and evaluated for inhibition of the E. coli enzyme.
P Pacaud et al.
The Journal of physiology, 441, 477-499 (1991-09-01)
1. The action of carbachol, which activates muscarinic receptors, was studied in single patch-clamped cells where free internal calcium concentration in the cell (Cai2+) was estimated using the emission from the dye Indo-1. Cells were dialysed with potassium-free caesium solution
Nisreen Wahwah et al.
Scientific reports, 10(1), 19907-19907 (2020-11-18)
Cisplatin is a mainstay of cancer chemotherapy. It forms DNA adducts, thereby activating poly(ADP-ribose) polymerases (PARPs) to initiate DNA repair. The PARP substrate NAD+ is synthesized from 5-phosphoribose-1-pyrophosphate (PRPP), and we found that treating cells for 6 h with cisplatin reduced
Matthew Bratkowski et al.
Cell reports, 32(5), 107999-107999 (2020-08-07)
The NADase SARM1 is a central switch in injury-activated axon degeneration, an early hallmark of many neurological diseases. Here, we present cryo-electron microscopy (cryo-EM) structures of autoinhibited (3.3 Å) and active SARM1 (6.8 Å) and provide mechanistic insight into the tight regulation
Boyuan Wang et al.
Molecular cell, 80(1), 29-42 (2020-08-29)
(p)ppGpp is a nucleotide messenger universally produced in bacteria following nutrient starvation. In E. coli, ppGpp inhibits purine nucleotide synthesis by targeting several different enzymes, but the physiological significance of their inhibition is unknown. Here, we report the structural basis of
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