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Merck
모든 사진(1)

주요 문서

G1049

Sigma-Aldrich

Poly-L-γ-glutamic acid sodium salt

suitable for drug transporter assays, Mol wt ≥750,000

동의어(들):

γ-PGA

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크기 선택

100 MG
₩471,468

₩471,468

구입 가능 여부는 고객센터에 문의하십시오.
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모든 사진(1)

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100 MG
₩471,468

About This Item

CAS Number:
208106-41-6
MDL number:
MFCD00081868
UNSPSC 코드:
12352209
NACRES:
NA.26

₩471,468

구입 가능 여부는 고객센터에 문의하십시오.
벌크 견적 요청

제품명

Poly-L-γ-glutamic acid sodium salt,

양식

powder

분자량

≥750,000

기술

drug transporter assay: suitable

색상

white to off-white

응용 분야

cell analysis

저장 온도

−20°C

관련 카테고리

애플리케이션

High molecular weight poly-γ-glutamic acid (γPGA) was found to increase levels of NK cell-mediated cytotoxicity and INF-γ secretion in C57BL/6 mice.[1] Biodegradable γ-PGA nanoparticles have been evaluated for use as antigen delivery carriers[2] and delivery of influenza virus hemagglutin (HA) vaccine.[3] Additional life science applications for γ-PGA include uses in biodegradable fibers and nanofiber sheets, hydrogels, and cryoprotectants.[4][5][6]

기타 정보

High molecular weight poly-γ-glutamic acid is a polymer of glutamic acid connected by amide linkages between α-amino and γ-carboxylic acid groups. γ-PGA is produced by fermentation in Bacillus species. The subunits are predominantly L-isomer.

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point (°F)

Not applicable

Flash Point (°C)

Not applicable

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시험 성적서(COA)

Lot/Batch Number
MKCV0152
MKCQ9820
MKCR5164
MKCN8813
MKCL8712

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COA 검색

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문서 라이브러리 방문

이미 열람한 고객

Slide 1 of 2

1 of 2

Polyglycolide inherent viscosity 1.4dL/g

Sigma-Aldrich

457620

Polyglycolide

L-Phenylalanine ethyl ester hydrochloride 99%

Sigma-Aldrich

220701

L-Phenylalanine ethyl ester hydrochloride

Preparation and evaluation of poly(γ-glutamic acid)-based anti-adhesion membranes.
Kim, Y.-A., et al.
Key Engineering Materials, 342, 225-225 (2007)
The utility of poly(γ-glutamic acid) nanoparticles as antigen delivery carriers in dendritic cell-based cancer immunotherapy.
Matsuo, K., et al.
Biological & Pharmaceutical Bulletin, 33, 2007-2007 (2010)
Shigefumi Okamoto et al.
Vaccine, 27(42), 5896-5905 (2009-08-04)
Adding poly(gamma-glutamic acid) nano-particles (gamma-PGA-NPs), a safe, natural material, to subcutaneous immunization with influenza virus hemagglutinin (HA) vaccine increases the protective immune responses against influenza virus in mice. Here, we examined whether intranasal administration of the HA vaccine with gamma-PGA-NPs
Ilaria Massaiu et al.
Microbial cell factories, 18(1), 3-3 (2019-01-11)
Genome-scale metabolic models (GEMs) allow predicting metabolic phenotypes from limited data on uptake and secretion fluxes by defining the space of all the feasible solutions and excluding physio-chemically and biologically unfeasible behaviors. The integration of additional biological information in genome-scale models
Tae Woo Kim et al.
Journal of immunology (Baltimore, Md. : 1950), 179(2), 775-780 (2007-07-10)
We analyzed the in vivo tumor regression activity of high molecular mass poly-gamma-glutamate (gamma-PGA) from Bacillus subtilis sups. chungkookjang. C57BL/6 mice were orally administered 10-, 100-, or 2000-kDa gamma-PGA or beta-glucan (positive control), and antitumor immunity was examined. Our results
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질문

1–3 / 3 질문  

  1. How is shipping temperature determined? And how is it related to the product storage temperature?

    1 답변

    1. Products may be shipped at a different temperature than the recommended long-term storage temperature. If the product quality is sensitive to short-term exposure to conditions other than the recommended long-term storage, it will be shipped on wet or dry-ice. If the product quality is NOT affected by short-term exposure to conditions other than the recommended long-term storage, it will be shipped at ambient temperature. As shipping routes are configured for minimum transit times, shipping at ambient temperature helps control shipping costs for our customers. For more information, please refer to the Storage and Transport Conditions document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/316/622/storage-transport-conditions-mk.pdf

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  2. How can I determine the shelf life / expiration / retest date of this product?

    1 답변

    1. If this product has an expiration or retest date, it will be shown on the Certificate of Analysis (COA, CofA). If there is no retest or expiration date listed on the product's COA, we do not have suitable stability data to determine a shelf life. For these products, the only date on the COA will be the release date; a retest, expiration, or use-by-date will not be displayed.
      For all products, we recommend handling per defined conditions as printed in our product literature and website product descriptions. We recommend that products should be routinely inspected by customers to ensure they perform as expected.
      For products without retest or expiration dates, our standard warranty of 1 year from the date of shipment is applicable.
      For more information, please refer to the Product Dating Information document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/449/386/product-dating-information-mk.pdf

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  3. Is G1049 product free of endotoxin? 

    1 답변

    1. Unfortunately, this product is not tested to determine endotoxin.

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