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Merck
모든 사진(3)

문서

P7908

Sigma-Aldrich

N-(1-Pyrenyl)maleimide

동의어(들):

1-(1-Pyrenyl)-1H-pyrrole-2,5-dione

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모든 사진(3)

About This Item

실험식(Hill 표기법):
C20H11NO2
CAS Number:
42189-56-0
Molecular Weight:
297.31
Beilstein:
1542661
EC Number:
255-702-1
MDL number:
MFCD00049301
UNSPSC 코드:
12352100
PubChem Substance ID:
24898892
NACRES:
NA.22

형태

powder

mp

235-237 °C (lit.)

SMILES string

O=C1C=CC(=O)N1c2ccc3ccc4cccc5ccc2c3c45

InChI

1S/C20H11NO2/c22-17-10-11-18(23)21(17)16-9-7-14-5-4-12-2-1-3-13-6-8-15(16)20(14)19(12)13/h1-11H

InChI key

YXKWRQLPBHVBRP-UHFFFAOYSA-N

유사한 제품을 찾으십니까? 방문 제품 비교 안내

관련 카테고리

애플리케이션

Reactant used in synthesis of:
  • Oligodeoxynucleotide derivatives
  • Polymer conjugates of immunogenic peptides
  • Modified oligonucleotides for biosensing applications,

Reactant:
  • Involved in synthesis of thermally stable fluorescent maleimide/isobutene alternating copolymers
  • Used as derivitizing agent for determination of glutathione disulfide levels in biological samples

포장

Bottomless glass bottle. Contents are inside inserted fused cone.

픽토그램

Exclamation mark
GHS07

신호어

Warning

유해 및 위험 성명서

H315,H319,H335

예방조치 성명서

P302 + P352 - P305 + P351 + P338

Hazard Classifications

Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

표적 기관

Respiratory system

Storage Class Code

11 - Combustible Solids

WGK

WGK 1

Flash Point (°F)

Not applicable

Flash Point (°C)

Not applicable

개인 보호 장비

dust mask type N95 (US), Eyeshields, Gloves

시험 성적서(COA)

제품의 로트/배치 번호를 입력하여 시험 성적서(COA)을 검색하십시오. 로트 및 배치 번호는 제품 라벨에 있는 ‘로트’ 또는 ‘배치’라는 용어 뒤에서 찾을 수 있습니다.

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문서 라이브러리 방문

이미 열람한 고객

Slide 1 of 3

1 of 3

1-Pyrenebutyric hydrazide for fluorescence, ≥97.0% (T)

Sigma-Aldrich

82669

1-Pyrenebutyric hydrazide

N-tert-Butylmaleimide 97%

Sigma-Aldrich

386421

N-tert-Butylmaleimide

N-Phenylmaleimide 97%

Sigma-Aldrich

P27100

N-Phenylmaleimide

V Guixé
Archives of biochemistry and biophysics, 376(2), 313-319 (2000-04-25)
Modification of Escherichia coli phosphofructokinase-2 (Pfk-2) with N-(1-pyrenil)maleimide results in an enzyme form that is inactive. However, the rate of modification is drastically reduced in the presence of the allosteric effector MgATP. The stoichiometry of the label incorporation was found
Pei-Rong Huang et al.
Molecular biology reports, 39(9), 8899-8905 (2012-06-19)
Telomerase activity is repressed in normal human somatic cells, but is activated in most cancers, suggesting that telomerase may be an important target for cancer therapy. Agents that interact selectively with telomerase are anticipated to exert specific action on cancer
Mateja Mancek-Keber et al.
The Journal of biological chemistry, 284(29), 19493-19500 (2009-05-29)
MD-2 is a part of the Toll-like 4 signaling complex with an indispensable role in activation of the lipopolysaccharide (LPS) signaling pathway and thus a suitable target for the therapeutic inhibition of TLR4 signaling. Elucidation of MD-2 structure provides a
Mauricio Baez et al.
The Biochemical journal, 376(Pt 1), 277-283 (2003-08-21)
Modification of Escherichia coli phosphofructokinase-2 (Pfk-2) with pyrene maleimide (PM) results in a rapid inactivation of the enzyme. The loss of enzyme activity correlates with the incorporation of 2 mol of PM/mol of subunit and the concomitant dissociation of the
Rajam S Mani et al.
Biochemistry, 45(11), 3534-3541 (2006-03-15)
Human deoxycytidine kinase (dCK) phosphorylates both pyrimidine and purine deoxynucleosides, including numerous nucleoside analogue prodrugs. Energy transfer studies of transfer between Trp residues of dCK and the fluorescent probe N-(1-pyrene)maleimide (PM), which specifically labels Cys residues in proteins, were performed.
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