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N7653

Sigma-Aldrich

p-Nitrophenyl Phosphate Liquid Substrate System

alkaline phosphatase substrate, liquid

동의어(들):

4-Nitrophenyl phosphate disodium salt solution, pNPP

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크기 선택

100 ML
₩263,900

₩263,900

출고 가능일2025년 4월 07일세부사항

모든 사진(3)

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100 ML
₩263,900

About This Item

Linear Formula:
O2NC6H4OP(O)(ONa)2
CAS Number:
4264-83-9
Molecular Weight:
263.05
MDL number:
MFCD00007319
UNSPSC 코드:
12352204
PubChem Substance ID:
24897835
NACRES:
NA.83

₩263,900

출고 가능일2025년 4월 07일세부사항

제품명

p-Nitrophenyl Phosphate Liquid Substrate System, liquid

양식

liquid

배송 상태

wet ice

저장 온도

−20°C

SMILES string

[Na+].[Na+].[O-][N+](=O)c1ccc(OP([O-])([O-])=O)cc1

InChI

1S/C6H6NO6P.2Na/c8-7(9)5-1-3-6(4-2-5)13-14(10,11)12;;/h1-4H,(H2,10,11,12);;/q;2*+1/p-2

InChI key

VIYFPAMJCJLZKD-UHFFFAOYSA-L

관련 카테고리

일반 설명

The p-Nitrophenyl Phosphate (pNPP) Liquid Substrate System combines p-nitrophenyl phosphate, buffer, and the required magnesium cations in a convenient, ready-to-use, single solution reagent. Producing a soluble end product, pNPP is the substrate of choice in alkaline phosphatase enzyme immunoassays.[1]

애플리케이션

p-Nitrophenyl Phosphate Liquid Substrate System has been used as a substrate to determine the activity of alkaline phosphatase[2] in alkaline phosphatase assay.[3]
Substrate for alkaline phosphatase that yields a soluble yellow end product that may be read at 405 nm. The reaction may be stopped with 3N NaOH and read at 405 nm. Recommended for ELISA (microwell) procedures, not recommended for membrane applications.

생화학적/생리학적 작용

4-Nitrophenyl phosphate disodium salt hexahydrate (pNPP) is a non-proteinaceous and non-specific substrate for determining protein tyrosine phosphatase activity. Hydrolysis of pNPP produces p-nitrophenol.[4] It is a common chromogenic substrate for alkaline phosphatase.[5]

주의사항

Stable at least one year when stored below 0 °C.

물리적 형태

Ready-to-use.

픽토그램

Health hazardCorrosion
GHS08,GHS05

신호어

Danger

유해 및 위험 성명서

H290,H315,H318,H361fd,H373

Hazard Classifications

Eye Dam. 1 - Met. Corr. 1 - Repr. 2 - Skin Irrit. 2 - STOT RE 2 Oral

표적 기관

Kidney,Liver,Blood

Storage Class Code

8B - Non-combustible corrosive hazardous materials

WGK

WGK 3

Flash Point (°F)

Not applicable

Flash Point (°C)

Not applicable

가장 최신 버전 중 하나를 선택하세요:

시험 성적서(COA)

Lot/Batch Number
SLCN6783
SLCN6783
SLCL1721
SLCF2308
SLBP4121V

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As dual regulators, the PTP-1B signaling pathway and α-glucosidase slow glucose release and increase the degree of insulin sensitivity, representing a promising therapeutic target for type 2 diabetes. In this study, we systematically examined the in vivo and in vitro anti-diabetic activities
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모든 관련된 서류 보기

문서

Colorimetric Phosphatase/Peroxidase Substrate Systems

NBT-BCIP substrate system aids in western blotting and immunohistological staining, producing a blue-purple insoluble end product.

질문

1–4 / 4 질문  

  1. What type of application can Product N7653, p-Nitrophenyl Phosphate Liquid Substrate System, be used in?

    1 답변

    1. This product is recommended for ELISA (microwell) procedures and is not recommended for membrane applications.

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  2. How should Product N7653, p-Nitrophenyl Phosphate Liquid Substrate System, be used?

    1 답변

    1. Information on usage is found in our product information sheet (under Documents, above).

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  3. What is the concentration of Product N7653, p-Nitrophenyl Phosphate Liquid Substrate System?

    1 답변

    1. The concentration of this product is considered proprietary.

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  4. What is the Department of Transportation shipping information for this product?

    1 답변

    1. Transportation information can be found in Section 14 of the product's (M)SDS.To access the shipping information for this material, use the link on the product detail page for the product.

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