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Merck
모든 사진(1)

주요 문서

N5254

Sigma-Aldrich

Neuraminidase Agarose from Clostridium perfringens (C. welchii)

Type VI-A, ammonium sulfate suspension

동의어(들):

Acylneuraminyl hydrolase, Receptor-destroying enzyme, Sialidase

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About This Item

효소 위원회 번호:
MDL number:
UNSPSC 코드:
12352204
NACRES:
NA.54
가격 및 재고 정보를 현재 이용할 수 없음 고객지원팀으로 연락바랍니다.

유형

Type VI-A

Quality Level

양식

ammonium sulfate suspension

특이 활성도

20-60 units/g agarose

라벨링 범위

0.6-1.8 units per mL gel
20-60 units per g agarose

Matrix

beaded agarose

저장 온도

2-8°C

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일반 설명

Neuraminidase enzymes are glycoside hydrolase enzymes that catalyze hydrolysis of terminal sialic acid residues. The most well-known are the viral nearamidases, which promote influenza virus release.

애플리케이션

Agarose-linked neuraminidase from Clostridium perfringens can be used for the detection of total and desialylated sex hormone-binding globulin in human serum samples. [1]
Neuraminidase from Clostridium perfringens has been used in a study to assess a genetic polymorphism of human serum glycoprotein (inter-α-trypsin-inhibitor). [2] It has also been used in a study to investigate the inhibition of neuraminidase by chemically sulphated glycopeptides. [3]

단위 정의

One unit will liberate 1.0 μmole of N-acetylneuraminic acid per min at pH 5.0 at 37 °C using NAN-lactose or bovine submaxillary mucin, unless otherwise specified. Prices based on units using NAN-lactose as substrate.

물리적 형태

Suspension in 2.0 M (NH4)2SO4 solution, pH 7.0.

제조 메모

Prepared from Neuraminidase, Type VI (N 3001).

Storage Class Code

12 - Non Combustible Liquids

WGK

WGK 3

Flash Point (°F)

Not applicable

Flash Point (°C)

Not applicable


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문서 라이브러리 방문

The mechanisms controlling the recognition of tumor- and virus-infected cells by NKp46
Arnon, T.I., et al
Immunobiol., 103(2), 664-672 (2004)
T I Arnon et al.
European journal of immunology, 31(9), 2680-2689 (2001-09-06)
Natural killer (NK) cells destroy virus-infected and tumor cells without prior antigen stimulation. The NK cell cytotoxicity is regulated in large part by the expression of NK cell receptors that are able to bind major histocompatibility complex (MHC) class I
N Mian et al.
The Biochemical journal, 181(2), 377-385 (1979-08-01)
Chemically sulphated glycopeptides (derived from pig duodenal mucosa) inhibited Clostridium perfringens neuraminidase (EC 3.2.1.18) activity in a pH-dependent manner. Analysis of inhibition kinetics data indicated that, although the enzyme inhibition could not be categorized into any of the classical types
U Vogt et al.
Human genetics, 84(2), 151-154 (1990-01-01)
A new genetic polymorphism of a human serum glycoprotein, the inter-alpha-trypsin-inhibitor (ITI), has been demonstrated by population and family studies. Sera were examined after neuraminidase treatment by isoelectric focusing on agarose gels followed by immunoblotting or by immunofixation with specific
Measurements of total and desialylated sex hormone binding globulin in serum by ELISA.
J Vaysse et al.
Clinical chemistry, 44(4), 882-884 (1998-04-29)

문서

Understand sialic acid structure, function, signaling, and modifications. Easily find products for sialic acid research.

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