MAK530

Alkaline Phosphatase (ALP) Assay Kit

sufficient for 100 fluorometric tests

• 동의어(들): Fluorometric Alkaline Phosphatase Assay Kit
• UNSPSC 코드: 12161503
• NACRES: NA.84

속성

• Quality Level: 100
• 응용 분야: pharmaceutical
• 검출 방법: fluorometric
• 관련 질환(들): cancer; neurological disorders; gastrointestinal diseases; genitourinary disorders
• 배송 상태: wet ice
• 저장 온도: −20°C

설명

일반 설명

Alkaline phosphatase (ALP) catalyzes the hydrolysis of phosphate esters in an alkaline environment, resulting in the formation of an organic radical and inorganic phosphate. In mammals, this enzyme is found mainly in the liver and bones. Marked increase in serum ALP levels, a disease known as hyperalkalinephosphatasemia, has been associated with malignant biliary obstruction, primary biliary cirrhosis, primary sclerosing cholangitis, hepatic lymphoma and sarcoidosis.

특징 및 장점

• Detection limit of 0.02 U/L
• Compatible with high-throughput handling systems.

적합성

The kit is suitable for ALP activity in serum, plasma and other sources, characterization and quality control for ALP production, and for high-throughput screening for ALP modulators.

원리

The Alkaline Phosphatase (ALP) Assay Kit utilizes 4-methylumbelliferyl phosphate that is hydrolyzed by ALP into the highly fluorescent product 4methylumbelliferone. The rate of the fluorescence increase is directly proportional to the enzyme activity.

안전성 정보

• 픽토그램: GHS05
• 신호어: Danger
• 유해 및 위험 성명서: H318
• 예방조치 성명서: P280 - P305 + P351 + P338
• Hazard Classifications: Eye Dam. 1
• Storage Class Code: 10 - Combustible liquids
• WGK: WGK 1