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Merck
모든 사진(1)

주요 문서

M7920

Sigma-Aldrich

Minoxidil Sulfate

동의어(들):

U-58838

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크기 선택

1 MG
₩138,345
5 MG
₩386,106

₩138,345


출고 가능일2025년 4월 10일세부사항


벌크 견적 요청

크기 선택

보기 변경
1 MG
₩138,345
5 MG
₩386,106

About This Item

실험식(Hill 표기법):
C9H15N5O4S
CAS Number:
Molecular Weight:
289.31
MDL number:
UNSPSC 코드:
12352107
PubChem Substance ID:
NACRES:
NA.77

₩138,345


출고 가능일2025년 4월 10일세부사항


벌크 견적 요청

양식

powder

주관자

Johnson & Johnson

저장 온도

−20°C

SMILES string

Nc1cc(nc(N)[n+]1OS([O-])(=O)=O)N2CCCCC2

InChI

1S/C9H15N5O4S/c10-7-6-8(13-4-2-1-3-5-13)12-9(11)14(7)18-19(15,16)17/h6H,1-5H2,(H4,10,11,12,15,16,17)

InChI key

OEOLOEUAGSPDLT-UHFFFAOYSA-N

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애플리케이션

Minoxidil sulfate (MXS) has been used as a drug agent to study its effects on alopecia in corticotropin-releasing factor over-expressing (CRF-OE) mice.[1] It has also been used as a positive control in an assay for the culturing of rat vibrissa follicles.[2]

생화학적/생리학적 작용

Minoxidil sulfate (MXS) is an endogenous derivative of minoxidil. It possesses greater aqueous solubility and is a potent vasodilator. MXS has the potential to treat androgenic alopecia or male baldness.[3]

특징 및 장점

This compound was developed by Johnson & Johnson. To browse the list of other pharma-developed compounds and Approved Drugs/Drug Candidates, click here.

기타 정보

Active metabolite of minoxidil.

픽토그램

Exclamation mark

신호어

Warning

유해 및 위험 성명서

Hazard Classifications

Acute Tox. 4 Oral - Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

표적 기관

Respiratory system

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

개인 보호 장비

dust mask type N95 (US), Eyeshields, Gloves


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문서 라이브러리 방문

U Russ et al.
British journal of pharmacology, 122(6), 1119-1126 (1997-12-24)
1. The ATP-sensitive K+ channel (KATP channel) in A10 cells, a cell line derived from rat thoracic aorta, was characterized by binding studies with the tritiated KATP channel opener, [3H]-P1075, and by electrophysiological techniques. 2. Saturation binding experiments gave a
Guilherme Martins Gelfuso et al.
Journal of microencapsulation, 28(7), 650-658 (2011-08-10)
Given the hypothesis that microparticles can penetrate the skin barrier along the transfollicular route, this work aimed to obtain and characterise chitosan microparticles loaded with minoxidil sulphate (MXS) and to study their ability to sustain the release of the drug
S Hayashi et al.
The Journal of pharmacology and experimental therapeutics, 265(3), 1527-1533 (1993-06-01)
Patch-clamp techniques were used to study pharmacological effects of minoxidil sulfate (MNXS) on the membrane currents of enzymatically isolated guinea pig ventricular myocytes. In the whole-cell current-clamp mode, MNXS (100 microM) shortened the action potential duration without affecting the resting
F M Ashcroft et al.
Trends in pharmacological sciences, 21(11), 439-445 (2000-12-21)
K(ATP) channel openers are a diverse group of drugs with a wide range of potential therapeutic uses. Their molecular targets, the K(ATP) channels, exhibit tissue-specific responses because they possess different types of regulatory sulfonylurea receptor subunits. It is well recognized
K D Meisheri et al.
Journal of vascular research, 30(1), 2-12 (1993-01-01)
This study in isolated rabbit superior artery (RMA) investigated the interactions between glyburide, a known blocker of vascular ATP-sensitive K+ channels (KATP), and several chemically diverse potassium channel openers (PCOs): minoxidil sulfate (MNXS; 5 microM), pinacidil (1 microM), cromakalim (0.5

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