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Merck
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주요 문서

M1778

Sigma-Aldrich

Mucin from porcine stomach

Type III, bound sialic acid 0.5-1.5 %, partially purified powder

동의어(들):

MUC

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크기 선택

10 G
₩184,426
100 G
₩764,904

₩184,426


예상 입고일2025년 4월 14일세부사항


벌크 견적 요청

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보기 변경
10 G
₩184,426
100 G
₩764,904

About This Item

CAS Number:
EC Number:
MDL number:
UNSPSC 코드:
12352202
NACRES:
NA.61

₩184,426


예상 입고일2025년 4월 14일세부사항


벌크 견적 요청

생물학적 소스

Porcine stomach

유형

Type III

양식

partially purified powder

구성

bound sialic acid, 0.5-1.5%

기술

microbiological culture: suitable

solubility

NaOH: soluble 20 mg/mL

저장 온도

2-8°C

유사한 제품을 찾으십니까? 방문 제품 비교 안내

일반 설명

Mucins or mucus glycoproteins are the main macromolecular components of mammalian mucus.[1] It was also used in a study to evaluate the sputum smears concentrated by cyto-centrifugation for detection of acid-fast bacilli.[2]

애플리케이션

Mucin from porcine stomach was used in studies on the binding site of the galactose-specific agglutinin PA-IL from Pseudomonas aeruginosa.[3]

생화학적/생리학적 작용

Mucus forms the protective cover for all epithelial surfaces. The major structural component of mucus is gel-forming mucins. The mucus layer covering the intestinal epithelium has the MUC2 mucin as its central molecule. MUC2 is produced by goblet cells.[4]

제조 메모

Prepared according to the method of Glenister, et al., for use in complex growth media for dental plaque bacteria.

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point (°F)

Not applicable

Flash Point (°C)

Not applicable

개인 보호 장비

Eyeshields, Gloves, type N95 (US)


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문서 라이브러리 방문

이미 열람한 고객

Kenny C Mok et al.
mBio, 11(6) (2020-12-10)
The beneficial human gut bacterium Akkermansia muciniphila provides metabolites to other members of the gut microbiota by breaking down host mucin, but most of its other metabolic functions have not been investigated. A. muciniphila strain MucT is known to use
Leyuan Li et al.
Microbiome, 8(1), 33-33 (2020-03-13)
Human-targeted drugs may exert off-target effects or can be repurposed to modulate the gut microbiota. However, our understanding of such effects is limited due to a lack of rapid and scalable assay to comprehensively assess microbiome responses to drugs. Drugs
C A Saceanu et al.
Journal of clinical microbiology, 31(9), 2371-2374 (1993-09-01)
Early identification and isolation of tuberculosis patients is of utmost importance to minimize the risk of further epidemic spread of the disease. The traditional concentrated acid-fast smears are not very reliable tools for the presumptive diagnosis of tuberculosis. Acid-fast bacillus
Francisco J Alvarez et al.
Applied and environmental microbiology, 81(8), 2770-2780 (2015-02-11)
The pathogenic fungus Candida albicans is the leading cause of vulvovaginal candidiasis (VVC). VVC represents a major quality-of-life issue for women during their reproductive years, a stage of life where the vaginal epithelium is subject to periodic hormonally induced changes
Anastasia Matthies et al.
Applied and environmental microbiology, 74(15), 4847-4852 (2008-06-10)
The metabolism of isoflavones by gut bacteria plays a key role in the availability and bioactivation of these compounds in the intestine. Daidzein and genistein are the most common dietary soy isoflavones. While daidzein conversion yielding equol has been known

문서

Understand sialic acid structure, function, signaling, and modifications. Easily find products for sialic acid research.

질문

1–7 / 7 질문  
  1. Can I reconstitute the mucin so that it forms a saliva/snot-like substance? I can't seem to find any papers that have done this...

    1 답변
    1. Mucins are soluble in water, forming hazy viscous solutions.

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  2. What does the "Type" designation in Mucin from porcine stomach mean?

    1 답변
    1. The type designation does not have any particular biological significance.  It is used to emphasize differences in the listings of this product.

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  3. What are the differences between Mucin from porcine stomach Products M2378 and M1778?

    1 답변
    1. Product No. M2378 is a crude mucin preparation. Product No. M1778 is a partially purified powder prepared according to the method described in Glenister, D.A. and Salmon. K. Microbial Ecol. in Health & Disease 1, 31, (1988). The amount of bound sialic acids are also different. Please refer to the specification sheets on our website.

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  4. Is Product M1778, Mucin from porcine stomach, a purified preparation of mucin?

    1 답변
    1. This product is a partially purified preparation of mucin based on the method of Glenister cited on the product's webpage.

      도움이 되었습니까?

  5. What is the molecular weight of Product M1778, Mucin from porcine stomach?

    1 답변
    1. This product is partially purified from crude mucin, M2378.  Sigma has not determined the molecular weight of this product. Neither has the sugar and amino acid composition been determined.

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  6. How can I solubilize Product M1778, Mucin from porcine stomach?

    1 답변
    1. Mucin is not readily soluble in aqueous solutions. Turbid "solutions" will form at about 5 mg/mL in 0.1 M acetate buffer, pH 5.0. To try to increase the solubility, one might try further dilution and sonication, but we have not tried this in our labs.

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  7. What is the Department of Transportation shipping information for this product?

    1 답변
    1. Transportation information can be found in Section 14 of the product's (M)SDS.To access the shipping information for this material, use the link on the product detail page for the product.

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