M109
2-Methylserotonin maleate salt
≥98% (HPLC)
동의어(들):
2-Methyl-5-hydroxytryptamine maleate salt, 3-(2-Aminoethyl)-2-methyl-1H-indol-5-ol maleate salt
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모든 사진(1)
About This Item
실험식(Hill 표기법):
C11H14N2O · C4H4O4
CAS Number:
Molecular Weight:
306.31
MDL number:
UNSPSC 코드:
12352200
PubChem Substance ID:
추천 제품
분석
≥98% (HPLC)
형태
solid
색상
tan
solubility
H2O: 4.5 mg/mL
저장 온도
−20°C
SMILES string
OC(=O)\C=C/C(O)=O.Cc1[nH]c2ccc(O)cc2c1CCN
유전자 정보
human ... HTR3A(3359) , HTR3B(9177)
생화학적/생리학적 작용
5-HT3 serotonin receptor agonist.
Storage Class Code
13 - Non Combustible Solids
WGK
WGK 3
Flash Point (°F)
Not applicable
Flash Point (°C)
Not applicable
개인 보호 장비
Eyeshields, Gloves, type N95 (US)
시험 성적서(COA)
제품의 로트/배치 번호를 입력하여 시험 성적서(COA)을 검색하십시오. 로트 및 배치 번호는 제품 라벨에 있는 ‘로트’ 또는 ‘배치’라는 용어 뒤에서 찾을 수 있습니다.
T Endo et al.
Research communications in molecular pathology and pharmacology, 104(2), 145-155 (2000-01-14)
The object of this study was to evaluate the involvement of 5-HT3 receptors in the regulation of 5-HT release from the small intestine using ferrets, an animal model of emesis. 2-Methyl-5-HT, a 5-HT3 receptor agonist, produced a concentration-dependent increase of
D M Gillies et al.
European journal of pharmacology, 303(1-2), 1-12 (1996-05-06)
5-Hydroxytryptamine (5-HT) is involved in the modulation of dopaminergic activity in the mesolimbic system, but its sites of action and the receptors involved are not well understood. Locomotor activity responses in rats were monitored in Animex automated activity boxes following
A M Ismaiel et al.
Journal of medicinal chemistry, 33(2), 755-758 (1990-02-01)
alpha-Methyl-5-hydroxytryptamine (alpha-Me-5-HT; 2) and 2-methyl-5-hydroxytryptamine (2-Me-5-HT; 3) are considered to be 5-HT2-selective and 5-HT3-selective agents, respectively. These agents were synthesized and examined at serotonin (5-HT) binding sites because there is relatively little documentation as to their selectivity and because they
Weixia Zhong et al.
PloS one, 9(8), e104718-e104718 (2014-08-15)
Stimulation of 5-HT3 receptors (5-HT3Rs) by 2-methylserotonin (2-Me-5-HT), a selective 5-HT3 receptor agonist, can induce vomiting. However, downstream signaling pathways for the induced emesis remain unknown. The 5-HT3R channel has high permeability to extracellular calcium (Ca(2+)) and upon stimulation allows
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