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Merck
모든 사진(1)

주요 문서

L3262

Sigma-Aldrich

Anti-Lactoferrin antibody produced in rabbit

fractionated antiserum, lyophilized powder

동의어(들):

Anti-Draculin, Anti-Draculin-1

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About This Item

MDL number:
UNSPSC 코드:
12352203
NACRES:
NA.46

생물학적 소스

rabbit

Quality Level

결합

unconjugated

항체 형태

fractionated antiserum

항체 생산 유형

primary antibodies

클론

polyclonal

양식

lyophilized powder

종 반응성

human

포장

vial of 2 mL lyophilized antiserum

기술

direct ELISA: 1:10,000 using using human lactoferrin

UniProt 수납 번호

저장 온도

2-8°C

타겟 번역 후 변형

unmodified

유전자 정보

human ... LTF(4057)

일반 설명

Lactoferrin, globular glycoprotein belongs to transferrin protein family. It is mapped to human chromosome 3p21.31. Lactoferrin comprises 692 amino acids with two globular lobes linked by α-helix and belongs to transferrin family. It exists in three isoforms namely lactoferrin-α, lactoferrin-γ, and lactoferrin-β. Lactoferrin corresponds to a molecular weight of 80 kDa.

특이성

Rabbit polyclonal anti-lactoferrin antibody reacts with purified lactoferrin and human milk, but does not react with human serum proteins.

애플리케이션

Anti-Lactoferrin antibody produced in rabbit has been used in:
  • western blotting
  • indirect immunofluorescence
  • flow cytometry
  • enzyme-linked immunosorbent assay (ELISA)

생화학적/생리학적 작용

A primary function of lactoferrin is to bind and transport iron ions. However, lactoferrin is also an effective antibacterial, antiviral, antiparasitic, catalytic (RNA degrading), anti-cancer molecule. It elicits anti-inflammatory effects in asthma. It has immunomodulatory and anti-inflammatory functionality and is a potential protein nutraceutical.

물리적 형태

Lyophilized from 0.01 M phosphate buffered saline, pH 7.2

재구성

Reconstitute with 2 ml deionized water.

면책조항

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point (°F)

Not applicable

Flash Point (°C)

Not applicable

개인 보호 장비

Eyeshields, Gloves, type N95 (US)


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문서 라이브러리 방문

Allergens induce the release of lactoferrin by neutrophils from asthmatic patients
Fernandez-Delgado L, et al.
Testing, 10(10), e0141278-e0141278 (2015)
Genetic and epigenetic inactivation of LTF gene at 3p21. 3 in lung cancers
Iijima H, et al.
International Journal of Cancer. Journal International Du Cancer, 118(4), 797-801 (2006)
Neutrophil extracellular traps contain selected antigens of anti-neutrophil cytoplasmic antibodies
Panda R, et al.
Frontiers in Immunology, 8(2), 439-439 (2017)
Studying lactoferrin N-glycosylation
Karav S, et al.
International Journal of Molecular Sciences, 18(4), 870-870 (2017)
Unstimulated salivary flow, pH, proteins and oral health in patients with Juvenile Idiopathic Arthritis
Kobus A, et al.
BMC Oral Health, 17(1), 94-94 (2017)

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