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추천 제품
제품명
Interleukin-4 from mouse, IL-4, recombinant, expressed in E. coli, lyophilized powder, suitable for cell culture
생물학적 소스
mouse
재조합
expressed in E. coli
분석
≥98% (SDS-PAGE)
양식
lyophilized powder
효능
0.1-2.0 ng/mL ED50/EC50
품질
endotoxin tested
분자량
~13.5 kDa
포장
pkg of 5 μg
기술
cell culture | mammalian: suitable
불순물
<0.1 EU/μg
UniProt 수납 번호
저장 온도
−20°C
유전자 정보
mouse ... Il4(16189)
애플리케이션
생화학적/생리학적 작용
Interleukin-4 (IL-4) is a lymphokine with profound effects on the growth and differentiation of immunologically competent cells. IL-4 is also known as B cell stimulatory factor-1 (BSF-1), T cell growth factor-2 (TCGF-2) and mast-cell growth factor-2 (MCGF-2). Inhibits VEGF-induced and FGF-Basic-induced angiogenesis. IL-4 is a complex glycoprotein released by a subset of activated T cells. Treatment of IL-4 with specific glycosidases yields an active polypeptide. Human and mouse IL-4 share 50% amino acid sequence homology, but their biological actions are species-specific.
Interleukin-4, a lymphokine with profound effects on the growth and differentiation of immunologically competent cells, inhibits VEGF-induced and bFGF-induced angiogenesis. Human and mouse IL-4 share 50% amino acid sequence identity, but their biological actions are species-specific.
물리적 형태
Lyophilized, 0.2 μm filtered, with no additives.
분석 메모
The proliferative activity is tested in culture using mouse HT-2 cells.[4]
Storage Class Code
11 - Combustible Solids
WGK
WGK 2
Flash Point (°F)
Not applicable
Flash Point (°C)
Not applicable
개인 보호 장비
Eyeshields, Gloves, type N95 (US)
이미 열람한 고객
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Sharba S, et al.
Virulence, 10(1), 97-117 (2019)
R Fernandez-Botran et al.
The Journal of experimental medicine, 164(2), 580-593 (1986-08-01)
T cell-derived supernatants (SN) that contain B cell-stimulatory factor 1 (BSF-1) and lack IL-2 promote the growth of the IL-2-dependent T cell line, HT-2, as well as three other clones or lines of T cells that can provide help to
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The Journal of investigative dermatology, 134(8), 2122-2130 (2014-02-01)
Atopic dermatitis (AD) is generally regarded as a type 2 helper T (Th2)-mediated inflammatory skin disease. Although the number of IL-17A-producing cells is increased in the peripheral blood and in acute skin lesion of AD patients, the role of IL-17A
문서
Interleukins, released from leukocytes, include IL-1β playing crucial roles in inflammation, immune responses, and anti-tumor immunity.
활성 필터
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