I0879

Inosine 5′-triphosphate trisodium salt

≥95%

• 동의어(들): ITP
• 실험식(Hill 표기법): C₁₀H₁₂Na₃N₄O₁₄P₃
• CAS Number: 35908-31-7
• Molecular Weight: 574.11
• MDL number: MFCD00084678
• UNSPSC 코드: 41106305
• PubChem Substance ID: 24895910
• NACRES: NA.51

속성

• 분석: ≥95%
• 배송 상태: dry ice
• 저장 온도: −20°C
• SMILES string: [Na].OC1C(O)C(OC1COP(O)(=O)OP(O)(=O)OP(O)(O)=O)n2cnc3C(=O)N=CNc23
• InChI: 1S/C10H15N4O14P3.Na.H/c15-6-4(1-25-30(21,22)28-31(23,24)27-29(18,19)20)26-10(7(6)16)14-3-13-5-8(14)11-2-12-9(5)17;;/h2-4,6-7,10,15-16H,1H2,(H,21,22)(H,23,24)(H,11,12,17)(H2,18,19,20);;
• InChI key: RIERCUPIZLBNFQ-UHFFFAOYSA-N
• 유전자 정보: human ... HRAS(3265)

설명

애플리케이션

Inosine 5′-triphosphate (ITP) is used in studies on the impact of deamination of ATP and GTP by various enzymes and chemical processes. ITP may be used as a substrate to study the specificity and kinetics of nucleoside-5′-triphosphatase and ATPase. ITP is also used to study activation of various ATPases and GTPases.

Inosine 5′-triphosphate trisodium salt has been used to investigate its influence on the chromosome aberration rate, the mitotic rate, sister-chromatid exchange (SCE) frequency, the proportion of first (X1), second (X2) and third (X3) division metaphases of human peripheral lymphocytes.

생화학적/생리학적 작용

Inosine 5′-triphosphate (ITP) has the ability to support the initiation of effector system. It can prevent guanosine 5′-triphosphate (GTP) hydrolysis, that is catalysed by transducin (TD). ITP can proficiently induce secretion in permeabilized cells than GTP. Instead of GTP, ITP can be used for the initiation and the elongation steps of reovirus transcription. ITP can also replace GTP in the activation of G-protein.

제조 메모

Prepared from Bacterial ATP

안전성 정보

• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 3
• Flash Point (°F): Not applicable
• Flash Point (°C): Not applicable