추천 제품
재조합
expressed in E. coli
Quality Level
분석
≥95% (SDS-PAGE)
분자량
18 kDa
농도
~1 mg/mL
UniProt 수납 번호
저장 온도
−20°C
유전자 정보
hepatitis B virus ... HBVgp4(944568)
human ... HBVgp4(944568)
일반 설명
amino acids 1-183 of HBV core antigen.
생화학적/생리학적 작용
HBcAg core human is a capsid protein of hepatitis B virus (HBV). It acts as a viral factor for HBV clearance. HBcAg is implicated in viral replication.[1]
Hepatitis B virus core antigen (HBcAg) is a positive control for human HBV antibodies.In humans with chronic HBV (hepatitis B virus) infection, cytotoxic effects of blood T lymphocytes can be suppressed by incubating cells with antibodies against hepatitis B core antigen (HBcAg).[2] The antigen can also work as a T-cell independent antigen in athymic mice. However, it is an efficient immunogen, resulting in T-cell activation and increased anti-HBc levels.[3] High cytoplasmic/membranous expression of HBcAg is associated with increased liver inflammation.[4]
물리적 형태
Solution in 50% glycerol, 7.5 mM phosphate buffer, pH 7.2, 75 mM NaCl.
Storage Class Code
10 - Combustible liquids
WGK
WGK 1
Flash Point (°F)
Not applicable
Flash Point (°C)
Not applicable
Jun Hong et al.
Hepatology research : the official journal of the Japan Society of Hepatology, 38(4), 362-373 (2007-11-21)
This study was undertaken to investigate whether plasmacytoid dendritic cells (PDC) are involved in the generation of a higher proportion of CD4(+) and CD25(+) regulatory T (Treg) cells in chronic hepatitis B virus (HBV) infection compared with healthy patients. The
Hepatitis B virus nucleocapsid but not free core antigen controls viral clearance in mice
Lin YJ, et al.
Journal of Virology, 86(17), 9266-9273 (2012)
M Mondelli et al.
Journal of immunology (Baltimore, Md. : 1950), 129(6), 2773-2778 (1982-12-01)
Peripheral blood T lymphocytes from 21 patients with chronic HBV infection were incubated with autologous hepatocytes in a microcytotoxicity assay. Cytotoxicity was significantly increased in 13 cases, and in 12 of these the cytotoxic effect of the T lymphocytes was
J B Kurtz et al.
Journal of virological methods, 96(2), 127-132 (2001-07-11)
A measurable serological response to hepatitis C infection is delayed on average until 70 days after infection. In addition, it may not occur in some immunocompromised people. Detection of free hepatitis C (HCV) core antigen in blood has enabled diagnosis
Long Liu et al.
Journal of medical virology (2020-02-23)
Hepatitis B virus (HBV) chronically infects approximately 350 million people worldwide, and 600 000 deaths are caused by HBV-related hepatic failure. Golgi protein 73 (GP73) is a serum biomarker for liver diseases, including chronic hepatitis B. Here, we determine the effect
활성 필터
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