Dipeptidyl peptidase-4 (DPP4) is a serine type protease is also known as CD26 or adenosine deaminase binding protein. It is expressed in the plasma membranes of T cells and activated natural killer or B cells. Its expressions also have been found on a number of endothelial and differentiated epithelial cells.
면역원
Immunogen Sequence: GI # 4503367, sequence 547-610
Recombinant dipeptidylpeptidase IV (CD26, adenosine deaminase complexing protein 2)
애플리케이션
Anti-DPP4 antibody produced in chicken is suitable for immunocytochemistry and western blotting analysis at a dilution of 1:500, for tissue or cell staining at a dilution of 1:200.
생화학적/생리학적 작용
Dipeptidyl peptidase-4 (DPP4) is a protein encoded by the DPP4 gene in humans. The T cell activation molecule DPP4 is associated with a 43kDa protein. It is associated with multiple sclerosis (MS) pathophysiology. DPP4 interacts on the T cell surface along with adenosine deaminase (ADA). Mutation in DPP4 causes an X-linked Simpson-Golabi-Behmel syndrome.
물리적 형태
Solution in phosphate buffered saline containing 0.02% sodium azide.
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Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
European journal of biochemistry, 267(17), 5608-5613 (2000-08-22)
Dipeptidyl peptidase IV (DPPIV, EC 3.4.14.5) is a serine type protease with an important modulatory activity on a number of chemokines, neuropeptides and peptide hormones. It is also known as CD26 or adenosine deaminase (ADA; EC 3.5.4.4) binding protein. DPPIV
Science (New York, N.Y.), 261(5120), 466-469 (1993-07-23)
CD26, the T cell activation molecule dipeptidyl peptidase IV (DPPIV), associates with a 43-kilodalton protein. Amino acid sequence analysis and immunoprecipitation studies demonstrated that this 43-kilodalton protein was adenosine deaminase (ADA). ADA was coexpressed with CD26 on the Jurkat T
Simpson-Golabi-Behmel syndrome (SGBS) is an X-linked condition shown to be the result of deletions of the glypican-3 (GPC3) gene. GPC3 is a proteoglycan localized to the cell membrane via a glycosylphosphatidyl-inositol (GPI) anchor. To further elucidate the GPC3 function(s), we
Multiple sclerosis (MS) is a prototypic Th1/Th17 chronic autoimmune disease of the central nervous system. Dipeptidyl peptidase 4 (DPP4 or CD26) is a multifunctional molecule involved in autoimmune diseases' pathophysiology. We sought to integrate disparate pieces of data and analyze
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