G6752

Guanosine

≥98%

• 동의어(들): 9-(β-D-Ribofuranosyl)guanine, Guanine-9-β-D-ribofuranoside
• 실험식(Hill 표기법): C₁₀H₁₃N₅O₅
• CAS Number: 118-00-3
• Molecular Weight: 283.24
• Beilstein: 625911
• EC Number: 204-227-8
• MDL number: MFCD00010182
• UNSPSC 코드: 41106305
• PubChem Substance ID: 24895268
• NACRES: NA.51

속성

• 생물학적 소스: microbial
• Quality Level: 100
• 분석: ≥98%
• 형태: powder
• mp: 250 °C (dec.) (lit.)
• solubility: formic acid:water (1:1): 50 mg/mL, clear to very slightly hazy, colorless to faintly yellow
• SMILES string: [H]O[H].NC1=Nc2c(ncn2[C@@H]3O[C@H](CO)[C@@H](O)[C@H]3O)C(=O)N1
• InChI: 1S/C10H13N5O5/c11-10-13-7-4(8(19)14-10)12-2-15(7)9-6(18)5(17)3(1-16)20-9/h2-3,5-6,9,16-18H,1H2,(H3,11,13,14,19)/t3-,5-,6-,9-/m1/s1
• InChI key: NYHBQMYGNKIUIF-UUOKFMHZSA-N

설명

일반 설명

Guanosine is an aromatic organic molecule and a purine nucleoside. It is present in the cerebrospinal fluid, intestinal cells, blood-brain barrier and in brain microvessels.

애플리케이션

Guanosine has been used:

• as a reference standard for the analysis of glucosinolates by high-performance liquid chromatography with diode-array detection and electrospray ionization tandem mass spectrometry (HPLC-DAD-ESI/MS)
• as a component of Mouse Embryonic Fibroblasts (MEFs) culture
• as a standard for the detection of residual RNA contaminant in oil palm plant genome samples by HPLC

생화학적/생리학적 작용

Guanosine nucleoside elicits cellular effect as the guanine-based purinergic system. It modulates glutamate uptake by glutamate transporters. It may have neuroprotective functionality in central nervous system disorders. Guanosine promotes neurite arborization, outgrowth, proliferation and differentiation. Administration of guanosine replenished GTP and elicits protective function in renal ischemic injury.

안전성 정보

• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 2
• Flash Point (°F): Not applicable
• Flash Point (°C): Not applicable
• 개인 보호 장비: Eyeshields, Faceshields, Gloves, type P2 (EN 143) respirator cartridges