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Merck
모든 사진(3)

문서

U6381

Sigma-Aldrich

Uridine

BioUltra, ≥99%

동의어(들):

1-β-D-Ribofuranosyluracil, Uracil-1-β-D-ribofuranoside

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About This Item

실험식(Hill 표기법):
C9H12N2O6
CAS Number:
Molecular Weight:
244.20
Beilstein:
754902
EC Number:
MDL number:
UNSPSC 코드:
12352204
PubChem Substance ID:
NACRES:
NA.26

생물학적 소스

synthetic (organic)

제품 라인

BioUltra

분석

≥99%

형태

powder

불순물

≤0.016% Phosphorus (P)
≤0.1% Insoluble matter

무기 잔류물

≤0.2%

mp

163-167 °C (lit.)

solubility

H2O: 0.1 M, clear, colorless

양이온 미량물

Al: ≤0.0005%
Ca: ≤0.01%
Cu: ≤0.0005%
Fe: ≤0.003%
K: ≤0.005%
Mg: ≤0.003%
NH4+: ≤0.15%
Na: ≤0.02%
Pb: ≤0.005%
Zn: ≤0.0005%

SMILES string

OC[C@H]1O[C@H]([C@H](O)[C@@H]1O)N2C=CC(=O)NC2=O

InChI

1S/C9H12N2O6/c12-3-4-6(14)7(15)8(17-4)11-2-1-5(13)10-9(11)16/h1-2,4,6-8,12,14-15H,3H2,(H,10,13,16)/t4-,6-,7-,8-/m1/s1

InChI key

DRTQHJPVMGBUCF-XVFCMESISA-N

유전자 정보

mouse ... Uck1(22245)

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일반 설명

Uridine is a pyrimidine nucleoside which is crucial for the synthesis of RNA and membranes. It helps in normal cell function and growth by forming pyrimidine nucleotide -lipid conjugates.

애플리케이션

Uridine has been used to study the functional complementation of nucleoside hydrolase from a protozoan parasite and mammalian uridine phosphorylase on URH1 (uridine hydrolase) of Saccharomyces cerevisiae.
It has been used to check the effect of chronic uridine application on liver metabolism in mice.

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point (°F)

Not applicable

Flash Point (°C)

Not applicable

개인 보호 장비

Eyeshields, Gloves, type N95 (US)


시험 성적서(COA)

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문서 라이브러리 방문

Chronic Uridine Administration Induces Fatty Liver and Pre-Diabetic Conditions in Mice.
Urasaki Y, et al.
PLoS ONE, 11, e0146994-e0146994 (2016)
Purinergic and Pyrimidinergic Signalling: Molecular, Nervous and Urogenitary System Function
Handbook of Experimental Pharmacology (2013)
Saccharomyces cerevisiae URH1 (encoding uridine-cytidine N-ribohydrolase): functional complementation by a nucleoside hydrolase from a protozoan parasite and by a mammalian uridine phosphorylase.
Mitterbauer R, et al.
Applied and Environmental Microbiology, 68, 1336-1343 (2002)
Qi Qiu et al.
Nature methods, 17(10), 991-1001 (2020-09-02)
Single-cell RNA sequencing offers snapshots of whole transcriptomes but obscures the temporal RNA dynamics. Here we present single-cell metabolically labeled new RNA tagging sequencing (scNT-seq), a method for massively parallel analysis of newly transcribed and pre-existing mRNAs from the same
Ian E Crandall et al.
Journal of medicinal chemistry, 56(6), 2348-2358 (2013-02-16)
Resistance by Plasmodium falciparum to almost all clinically used antimalarial drugs requires the development of new classes of antimalarials. 6-Iodouridine (15), a novel and potent inhibitor of orotidine 5'-monophosphate decarboxylase (ODCase), exhibited efficacy in a mouse model infected by P.

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