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Merck
모든 사진(1)

문서

G5894

Sigma-Aldrich

Glutaminase from Escherichia coli

Grade VII, lyophilized powder, 500-1,500 units/mg protein

동의어(들):

L-Glutamine amidohydrolase

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About This Item

CAS Number:
효소 위원회 번호:
MDL number:
UNSPSC 코드:
12352204
NACRES:
NA.54

유형

Grade VII

Quality Level

형태

lyophilized powder

특이 활성도

500-1,500 units/mg protein

구성

Protein, ~10% Lowry

저장 온도

−20°C

유사한 제품을 찾으십니까? 방문 제품 비교 안내

생화학적/생리학적 작용

Glutaminase catalyzes the conversion of glutamine to glutamate.

결합

Chromatographically purified from Grade V

단위 정의

One unit will deaminate 1.0 μmole of L-glutamine per min at pH 4.9 at 37 °C.

물리적 형태

Lyophilized powder containing stabilizer and potassium succinate

Storage Class Code

11 - Combustible Solids

WGK

WGK 1

Flash Point (°F)

Not applicable

Flash Point (°C)

Not applicable

개인 보호 장비

Eyeshields, Gloves, type N95 (US)


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문서 라이브러리 방문

Krupa Shukla et al.
Journal of medicinal chemistry, 55(23), 10551-10563 (2012-11-16)
Bis-2-(5-phenylacetamido-1,2,4-thiadiazol-2-yl)ethyl sulfide (BPTES) is a potent and selective allosteric inhibitor of kidney-type glutaminase (GLS) that has served as a molecular probe to determine the therapeutic potential of GLS inhibition. In an attempt to identify more potent GLS inhibitors with improved
Natalie E Simpson et al.
Epigenetics, 7(12), 1413-1420 (2012-11-03)
The interplay of metabolism and epigenetic regulatory mechanisms has become a focal point for a better understanding of cancer development and progression. In this study, we have acquired data supporting previous observations that demonstrate glutamine metabolism affects histone modifications in
Katsutoshi Yuasa et al.
FEBS letters, 586(19), 3464-3470 (2012-09-18)
Chromatin loops formed between distant regulatory elements and promoters modulate gene expression. We identified a novel distant regulatory element located approximately 120kb downstream of the gls promoter, and examined its regulatory relevance to gls gene expression in C2C12 cells by
Catherine Qiurong Pan et al.
FEBS letters, 586(17), 2674-2691 (2012-06-20)
The BNIP-2 and Cdc42GAP Homology (BCH) domains constitute a new and expanding family of highly conserved scaffold protein domains that regulate Rho, Ras and MAPK signaling, leading to cell growth, apoptosis, morphogenesis, migration and differentiation. Such versatility is achieved via
N V Zharkova et al.
Biomeditsinskaia khimiia, 58(2), 220-223 (2012-06-26)
Acute alcohol intoxication in rats with alloxan diabetes is accompanied by the increase of urea and uric acid and by the decrease in free fatty acids in serum. In the liver of experimental animals the increase of activity of glutamate

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