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Merck
모든 사진(1)

주요 문서

F7751

Sigma-Aldrich

Fluoxymesterone

solid (photosensitive)

동의어(들):

11β,17β-Dihydroxy-9α-fluoro-17α-methyl-4-androsten-3-one, 9α-Fluoro-11β,17β-dihydroxy-17α-methylandrost-4-en-3-one, 9α-Fluoro-11β-hydroxy-17α-methyltestosterone

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About This Item

실험식(Hill 표기법):
C20H29FO3
CAS Number:
Molecular Weight:
336.44
EC Number:
MDL number:
UNSPSC 코드:
51111800
PubChem Substance ID:
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생물학적 소스

Porcine pancreas
bovine milk (other parts like skeletal muscle/bile/bone/connective tissue/skin)
microbial (Mycobacterium sp.)

양식

solid (photosensitive)

약물 제어

USDEA Schedule III; Home Office Schedule 4.2; regulated under CDSA - not available from Sigma-Aldrich Canada

기술

HPLC: suitable
gas chromatography (GC): suitable

색상

white

solubility

H2O: ≤0.5 mg/mL
45% (w/v) aq 2-hydroxypropyl-β-cyclodextrin: 6.4 mg/mL
ethanol: 7.3 mg/mL

응용 분야

forensics and toxicology
veterinary

배송 상태

ambient

저장 온도

room temp

SMILES string

[H][C@@]12CC[C@](C)(O)[C@@]1(C)C[C@H](O)[C@@]3(F)[C@@]2([H])CCC4=CC(=O)CC[C@]34C

InChI

1S/C20H29FO3/c1-17-8-6-13(22)10-12(17)4-5-15-14-7-9-19(3,24)18(14,2)11-16(23)20(15,17)21/h10,14-16,23-24H,4-9,11H2,1-3H3/t14-,15-,16-,17-,18-,19-,20-/m0/s1

InChI key

YLRFCQOZQXIBAB-RBZZARIASA-N

유전자 정보

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생화학적/생리학적 작용

Fluoxymesterone is an androgen and anabolic steroid.

픽토그램

Health hazard

신호어

Warning

유해 및 위험 성명서

예방조치 성명서

Hazard Classifications

Repr. 2

Storage Class Code

13 - Non Combustible Solids

WGK

WGK 3

Flash Point (°F)

Not applicable

Flash Point (°C)

Not applicable

개인 보호 장비

Eyeshields, Gloves, type P3 (EN 143) respirator cartridges


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문서 라이브러리 방문

Oscar J Pozo et al.
Journal of mass spectrometry : JMS, 43(3), 394-408 (2007-11-27)
The suitability of liquid chromatography tandem mass spectrometry (LC-MS/MS) and gas chromatography mass spectrometry (GC-MS) for the elucidation of fluoxymesterone metabolism has been evaluated. Electrospray ionization (ESI) and collision induced dissociation (CID) fragmentation in LC-MS/MS and electron impact spectra (EI)
S M Stanley et al.
Journal of chromatography. B, Biomedical sciences and applications, 704(1-2), 119-128 (1998-03-28)
In this study the equine metabolism of fluoxymesterone (9alpha-fluoro-11beta-17beta-dihydroxy-17alpha-meth ylandrost-4-ene-3-one) given orally has been investigated. The parent material was not detected, but two major 16-hydroxy metabolites which corresponded to a mono- and a di-hydroxylation product were evident. One of the
J Aisner et al.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 13(6), 1443-1452 (1995-06-01)
We sought to compare three doxorubicin-based therapies for metastatic breast cancer for response frequency, time to treatment failure (TTF), and survival. Women with metastatic breast cancer who had measurable disease, required laboratory tests, had received no prior chemotherapy for metastases
C Rose et al.
Breast cancer research and treatment, 61(2), 103-110 (2000-08-15)
The efficacy of combined endocrine therapy with tamoxifen (TAM), aminoglutethimide (AG), and hydrocortisone (H) or tamoxifen and fluoxymesterone (FLU) was evaluated against treatment with tamoxifen alone in 311 patients above 65 years of age with a first recurrence of a
L Del Mastro et al.
Breast cancer research and treatment, 43(2), 183-190 (1997-04-01)
The role of amenorrhea induced by chemotherapy in premenopausal women with early breast cancer is very controversial. Analyses by various authors of the effect of drug-induced amenorrhea (DIA) on treatment outcome have yielded conflicting results. In order to gain insight

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