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Merck
모든 사진(2)

문서

E7879

Sigma-Aldrich

β-Estradiol 17-acetate

≥99%

동의어(들):

1,3,5(10)-Estratriene-3,17β-diol 17-acetate, 3,17β-Dihydroxy-1,3,5(10)-estratriene 17-acetate

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About This Item

실험식(Hill 표기법):
C20H26O3
CAS Number:
Molecular Weight:
314.42
Beilstein:
2625732
MDL number:
UNSPSC 코드:
12352200
PubChem Substance ID:
NACRES:
NA.77

무균

non-sterile

분석

≥99%

형태

powder

solubility

chloroform: 50 mg/mL, clear, colorless to faintly brownish-yellow

배송 상태

ambient

저장 온도

room temp

SMILES string

CC(=O)O[C@H]1CC[C@H]2[C@@H]3CCc4cc(O)ccc4[C@H]3CC[C@]12C

InChI

1S/C20H26O3/c1-12(21)23-19-8-7-18-17-5-3-13-11-14(22)4-6-15(13)16(17)9-10-20(18,19)2/h4,6,11,16-19,22H,3,5,7-10H2,1-2H3/t16-,17-,18+,19+,20+/m1/s1

InChI key

QAHOQNJVHDHYRN-SLHNCBLASA-N

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애플리케이션

β-Estradiol 17-acetate has been used in body burden analyses, to study the effect of triclosan on an estuarine fish.

생화학적/생리학적 작용

β-Estradiol is a steroid hormone involved in a number of organ functions. It is significantly associated with brain functions including neuroprotection, neurogenesis and synaptic plasticity. β-Estradiol maintains bone homeostasis, and hence is preferred for osteoporosis therapy. 17-β-Estradiol is the most active estrogen generated in our body. During postmenopausal, 17-β-estradiol inhibits oxidative modification in low density lipoprotein. This indicates that estrogen replacement therapy might be useful in treating cardiovascular disease.

특징 및 장점

This compound is a featured product for ADME Tox research. Click here to discover more featured ADME Tox products. Learn more about bioactive small molecules for other areas of research at sigma.com/discover-bsm.

픽토그램

Health hazardEnvironment

신호어

Danger

유해 및 위험 성명서

Hazard Classifications

Aquatic Chronic 1 - Repr. 1B

Storage Class Code

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

WGK

WGK 3

개인 보호 장비

Eyeshields, Gloves, type P3 (EN 143) respirator cartridges


시험 성적서(COA)

제품의 로트/배치 번호를 입력하여 시험 성적서(COA)을 검색하십시오. 로트 및 배치 번호는 제품 라벨에 있는 ‘로트’ 또는 ‘배치’라는 용어 뒤에서 찾을 수 있습니다.

이 제품을 이미 가지고 계십니까?

문서 라이브러리에서 최근에 구매한 제품에 대한 문서를 찾아보세요.

문서 라이브러리 방문

이미 열람한 고객

Estrogen and the Vessel Wall, 38-38 (2003)
Bioactive Natural Products: Chemistry and Biology, 375-375 (2015)
Layer-by-Layer Films for Biomedical Applications, 517-517 (2014)
Accumulation of triclosan from diet and its neuroendocrine effects in Atlantic croaker (Micropogonias undulatus) under two temperature Regimes
Hedrick-Hopper TL, et al.
Marine Environmental Research, 112(51), 52-60 (2015)
Anna Höckerstedt et al.
Journal of lipid research, 43(3), 392-397 (2002-03-15)
It has been shown that estrogens need to be metabolized to their hydrophobic estrogen ester derivatives to act as antioxidants in lipoproteins. Data suggest that 17beta-estradiol (E(2)) becomes esterified in LCAT-induced reactions and the esters are transported from HDL particles

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