E6635

Ethylenediaminetetraacetic acid disodium salt dihydrate

Sigma Grade, suitable for plant cell culture, 98.5-101.5%

• 동의어(들): Disodium ethylenediaminetetraacetate dihydrate, EDTA disodium salt, EDTA-Na₂, Edathamil, Edetate disodium salt dihydrate, Sequestrene Na₂
• 실험식(Hill 표기법): C₁₀H₁₄N₂Na₂O₈ · 2H₂O
• CAS Number: 6381-92-6
• Molecular Weight: 372.24
• Beilstein: 3900609
• EC Number: 205-358-3
• UNSPSC 코드: 12352107
• PubChem Substance ID: 24894632
• NACRES: NA.77

속성

• Grade: Sigma Grade
• 분석: 98.5-101.5%
• 양식: powder
• 반응 적합성: reagent type: chelator
• 기술: cell culture | plant: suitable
• mp: 248 °C (dec.) (lit.)
• solubility: H₂O: soluble, clear, colorless
• SMILES string: O.O.O.O.[Na+].[Na+].[Na+].[Na+].OC(=O)CN(CCN(CC([O-])=O)CC([O-])=O)CC(O)=O.OC(=O)CN(CCN(CC(O)=O)CC([O-])=O)CC([O-])=O
• InChI: 1S/C10H16N2O8.2Na.2H2O/c13-7(14)3-11(4-8(15)16)1-2-12(5-9(17)18)6-10(19)20;;;;/h1-6H2,(H,13,14)(H,15,16)(H,17,18)(H,19,20);;;2*1H2/q;2*+1;;/p-2
• InChI key: OVBJJZOQPCKUOR-UHFFFAOYSA-L

설명

일반 설명

Ethylenediaminetetraacetic acid (EDTA) is an aminopolycarboxylic acid and a hexadentate ligand. It chelates with metal ions, especially with cations to form an octahedral complex.[1] Ethylenediaminetetraacetic acid disodium salt (EDTA) is a blood anticoagulant and contributes to the pathogenesis of pseudothrombocytopenia. It chelates with calcium in the blood and inhibits clotting and is routinely used in haematological tests.[2] It enhances the antibacterial activity of lysozyme.[3] EDTA used in chelation therapy chelates with calcium and favors dilation of artery, solubilisation of atheromatous plaques in atherosclerotic vascular disease.[4] EDTA chelation therapy may also protect from oxidative damage during blood and lipid peroxidation in liver fibrosis. [5]

애플리케이션

Chelator of divalent cations. Inhibits enzymes, such as metalloproteases, that require divalent cations for activity.

Ethylenediaminetetraacetic acid disodium salt dihydrate has been in seed germination trials of plant species[6] and in protein extraction from Moss, Physcomitrella paten.[7] It has also been used in lysis and vacuole buffer for the isolation of vacuoles from Petunia petals.[8]

안전성 정보

• 픽토그램: GHS08,GHS07
• 신호어: Warning
• 유해 및 위험 성명서: H332,H373
• 예방조치 성명서: P260 - P271 - P304 + P340 + P312 - P314 - P501
• Hazard Classifications: Acute Tox. 4 Inhalation - STOT RE 2 Inhalation
• 표적 기관: Respiratory Tract
• Storage Class Code: 13 - Non Combustible Solids
• WGK: WGK 2
• Flash Point (°F): Not applicable
• Flash Point (°C): Not applicable
• 개인 보호 장비: Eyeshields, Gloves, type N95 (US)