추천 제품
생물학적 소스
rabbit
Quality Level
결합
unconjugated
항체 형태
IgG fraction of antiserum
항체 생산 유형
primary antibodies
클론
polyclonal
양식
buffered aqueous solution
분자량
antigen 97 kDa
종 반응성
mouse, human
기술
microarray: suitable
western blot: 1:8,000 using NIH 3T3 mouse fibroblasts cell extract
UniProt 수납 번호
배송 상태
dry ice
저장 온도
−20°C
타겟 번역 후 변형
unmodified
유전자 정보
human ... MAPK7(5598)
mouse ... Mapk7(23939)
일반 설명
Extracellular signal-regulated kinase 5 (ERK5), also referred to as big-MAP kinase 1 (BMK1), is a protein that belongs to mitogen-activated protein kinases family and is expressed mainly in skeletal muscle, kidney, heart and placenta. ERK5 contains a distinct 400-amino acid C-terminal and loop-12 domain, which includes two proline-rich regions.
면역원
synthetic peptide corresponding to amino acids 789-802 of human ERK5.
애플리케이션
Anti-ERK5 (big-MAPK, BMK1) an0tibody produced in rabbit has been used in immunoblotting.
생화학적/생리학적 작용
Extracellular signal-regulated kinase 5 (ERK5) has a critical role in different cellular processes like differentiation, proliferation and survival. Anti-ERK5 (big-MAPK, BMK1) antibody can be used to study the differential tissue expression and intracellular localization of the MAP Kinase isoform in normal and neoplastic tissues.
물리적 형태
Solution in 0.01 M phosphate buffered saline, pH 7.4, containing 15 mM sodium azide.
면책조항
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
적합한 제품을 찾을 수 없으신가요?
당사의 제품 선택기 도구.을(를) 시도해 보세요.
Storage Class Code
10 - Combustible liquids
WGK
WGK 3
Flash Point (°F)
Not applicable
Flash Point (°C)
Not applicable
가장 최신 버전 중 하나를 선택하세요:
시험 성적서(COA)
Lot/Batch Number
An evolutionarily conserved pathway controls proteasome homeostasis
Rousseau A and Bertolotti A
Nature, 536(7615), 184-184 (2016)
Extracellular signal-regulated kinase 7 (ERK7), a novel ERK with a C-terminal domain that regulates its activity, its cellular localization, and cell growth
Abe MK, et al.
Molecular and Cellular Biology, 19(2), 1301-1312 (1999)
The role of ERK1, 2, and 5 in dopamine neuron survival during aging
Parmar MS, et al.
Neurobiology of Aging, 35(3), 669-679 (2014)
Rajinder S Sawhney et al.
Journal of cellular physiology, 219(1), 152-161 (2008-12-18)
In metastatic cancer, high expression levels of vitronectin (VN) receptors (integrins), FAK, and ERK5 are reported. We hypothesized that integrin-mediated ERK5 activation via FAK may play a pivotal role in cell adhesion, motility, and metastasis. ERK5 and FAK phosphorylation when
Y Kato et al.
Nature, 395(6703), 713-716 (1998-10-28)
Epidermal growth factor (EGF) induces cell proliferation in a variety of cell types by binding to a prototype transmembrane tyrosine kinase receptor. Ligation of this receptor by EGF activates Erk1 and Erk2, members of the mitogen-activated protein (MAP) kinase family
활성 필터
자사의 과학자팀은 생명 과학, 재료 과학, 화학 합성, 크로마토그래피, 분석 및 기타 많은 영역을 포함한 모든 과학 분야에 경험이 있습니다..
고객지원팀으로 연락바랍니다.
