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Merck
모든 사진(1)

문서

D6035

Sigma-Aldrich

Disopyramide phosphate salt

동의어(들):

α-Diisopropylaminoethyl-α-phenylpyridine-2-acetamide

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About This Item

Linear Formula:
C21H29N3O · H3PO4
CAS Number:
Molecular Weight:
437.47
EC Number:
MDL number:
UNSPSC 코드:
12352200
PubChem Substance ID:
NACRES:
NA.77

형태

solid

SMILES string

OP(O)(O)=O.CC(C)N(CCC(C(N)=O)(c1ccccc1)c2ccccn2)C(C)C

InChI

1S/C21H29N3O.H3O4P/c1-16(2)24(17(3)4)15-13-21(20(22)25,18-10-6-5-7-11-18)19-12-8-9-14-23-19;1-5(2,3)4/h5-12,14,16-17H,13,15H2,1-4H3,(H2,22,25);(H3,1,2,3,4)

InChI key

CGDDQFMPGMYYQP-UHFFFAOYSA-N

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관련 카테고리

애플리케이션

Disopyramide phosphate salt has been used as an internal standard for plasma sample analysis by mass spectrometry. It might be used as a test compound in a teratogenicity study.

생화학적/생리학적 작용

Disopyramide is found to stabilize the cell membrane by altering the action potential. It might act as an antiarrhythmic agent.
Class IA antiarrhythmic; sodium channel blocker

픽토그램

Exclamation mark

신호어

Warning

유해 및 위험 성명서

예방조치 성명서

Hazard Classifications

Acute Tox. 4 Oral

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

개인 보호 장비

dust mask type N95 (US), Eyeshields, Gloves


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문서 라이브러리 방문

0
Drugs for Pregnant and Lactating Women, 252-338 (2009)
Akihito Yamashita et al.
The Journal of toxicological sciences, 39(3), 453-464 (2014-05-23)
The zebrafish has been considered as a suitable animal model for drug discovery, especially for evaluation of the teratogenicity, due to their small size, rapid development, transparency, and developmental similarities to mammalian development. These features of zebrafish make it possible
Anthony A Fossa et al.
The Journal of pharmacology and experimental therapeutics, 302(2), 828-833 (2002-07-20)
QT interval prolongation of the electrocardiogram has been associated with the occurrence of life-threatening fatal ventricular arrhythmias. To understand the relationship between preclinical cardiac conduction assessment to clinical outcome, comparisons of free (unbound)-plasma drug concentrations and their associated effects in
Lansoprazole precipitated QT prolongation and torsade de pointes associated with disopyramide.
Hiroshi Asajima et al.
European journal of clinical pharmacology, 68(3), 331-333 (2011-09-08)
Katsuya Kajimoto et al.
The American journal of cardiology, 106(9), 1307-1312 (2010-10-30)
Negative inotropic agents are often administered to decrease the left ventricular (LV) pressure gradient in patients with obstructive hypertrophic cardiomyopathy (HC). Little information is available regarding comparisons of the effects on LV pressure gradient among negative inotropic agents. The present

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