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Merck
모든 사진(2)

주요 문서

D5207

Sigma-Aldrich

Doxycycline hyclate

powder, suitable for cell culture, BioReagent

동의어(들):

Doxycycline hyclate, α-6-Deoxy-5-hydroxytetracycline, Doxycycline hydrochloride hemiethanolate hemihydrate, Vibramycin Hyclate

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크기 선택

1 G
₩99,064
5 G
₩247,153
10 G
₩418,282

₩99,064


예상 입고일2025년 2월 04일세부사항


벌크 견적 요청

크기 선택

보기 변경
1 G
₩99,064
5 G
₩247,153
10 G
₩418,282

About This Item

실험식(Hill 표기법):
C22H24N2O8 · HCl · 0.5H2O · 0.5C2H6O
CAS Number:
Molecular Weight:
512.94
Beilstein:
5702728
MDL number:
UNSPSC 코드:
12352207
NACRES:
NA.22

₩99,064


예상 입고일2025년 2월 04일세부사항


벌크 견적 요청

제품명

Doxycycline hyclate, Suitable for Cell Culture

Quality Level

양식

powder

저장 온도

2-8°C

SMILES string

Cl[H].Cl[H].[H]O[H].CCO.C[C@@H]1C2[C@H](O)C3[C@H](N(C)C)C(O)=C(C(N)=O)C(=O)[C@@]3(O)C(O)=C2C(=O)c4c(O)cccc14.C[C@@H]5C6[C@H](O)C7[C@H](N(C)C)C(O)=C(C(N)=O)C(=O)[C@@]7(O)C(O)=C6C(=O)c8c(O)cccc58

InChI

1S/2C22H24N2O8.C2H6O.2ClH.H2O/c2*1-7-8-5-4-6-9(25)11(8)16(26)12-10(7)17(27)14-15(24(2)3)18(28)13(21(23)31)20(30)22(14,32)19(12)29;1-2-3;;;/h2*4-7,10,14-15,17,25,27-29,32H,1-3H3,(H2,23,31);3H,2H2,1H3;2*1H;1H2/t2*7-,10?,14?,15-,17-,22-;;;;/m00..../s1

InChI key

HALQELOKLVRWRI-ZVACAFRPSA-N

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일반 설명

General description
Chemical structure: tetracycline

Doxycycline hyclate belongs to the second generation of tetracycline antibiotics family. Doxycycline hyclate shows minimal side effects upon usage. It is effective for the treatment of recurrent aphthous stomatitis (RAS) and promotes speedy recovery.

애플리케이션

Doxycycline hyclate has been used for the induction of glioma cells and human embryonic kidney 293T cells (HEK293T).

Doxycycline hyclate is a synthetic oxytetracycline derivative. It has been used to eliminate Borrelia burgdorferi and Anaplasma phagocytophilum in rodent reservoirs and to eliminate Ixodes scapularis ticks. It is a broad spectrum inhibitor used to inhibit matrix metalloproteinases (MMP), such as type 1 collagenase in studies on wound healing and tissue remodeling.

생화학적/생리학적 작용

Doxycycline hyclate inhibits the inflammatory response to the Lyme Disease Spirochete Borrelia burgdorferi. It is a broad spectrum inhibitor of matrix metalloproteinases in vivo.
Mode of Action: Doxycycline hyclate inhibits the inflammatory response to the Lyme Disease Spirochete Borrelia burgdorferi.

Activity Spectrum: Effective against a broad spectrum inhibitor of matrix metalloproteinases in vivo.

포장

1, 5, 10 g in glass bottle

픽토그램

Health hazardExclamation mark

신호어

Warning

유해 및 위험 성명서

Hazard Classifications

Acute Tox. 4 Oral - Aquatic Chronic 3 - Eye Irrit. 2 - Repr. 2 - Skin Irrit. 2 - STOT SE 3

표적 기관

Respiratory system

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point (°F)

Not applicable

Flash Point (°C)

Not applicable


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문서 라이브러리 방문

질문

1–3 / 3 질문  
  1. What temperature should a solution be stored?

    1 답변
    1. As stated in the 'PROPERTIES' section, the recommended storage temperature for this product is 2–8 °C. Please see the link below to review additional information available in the product datasheet:
      https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/product/documents/402/297/d5207dat.pdf

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  2. Is this product suitable for in-vivo use (added to drinking water)? Also what is the difference between this product (D5207) and D9891? thank you

    1 답변
    1. This product is intended for research use only. It is not suitable for human or veterinary use. The material has not been tested in animal models for ingestion. The end user would need to determine suitability. The major difference between product D5207 and D9891 is the testing performed. Product D5207 is tested suitable for cell culture applications. Please see the product specification sheet below regarding testing:
      https://www.sigmaaldrich.com/specification-sheets/330/944/D5207-10G.pdf
      https://www.sigmaaldrich.com/specification-sheets/323/301/D9891-25G.pdf

      도움이 되었습니까?

  3. Hello. I have a question regarding the ref D5207 Doxycycline hyclate. I would like to know how I can resuspend the powder (DMSO, H2O, etc...). And at which concentration. Is that 10 mg/ml ok ? Thank you.

    1 답변
    1. This product is soluble in water (50 mg/mL), and in DMSO (10 mg/mL) yielding a clear solution. Mild warming may be required to fully dissolve the material.

      Please see the product data sheet for more information:
      https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/product/documents/402/297/d5207dat.pdf

      도움이 되었습니까?

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