B4750

N_α-Benzoyl-DL-arginine β-naphthylamide hydrochloride

trypsin substrate

• 동의어(들): BANA, N_α-Benzoyl-DL-arginine-2-naphthylamide hydrochloride
• 실험식(Hill 표기법): C₂₃H₂₅N₅O₂ · HCl
• CAS Number: 913-04-2
• Molecular Weight: 439.94
• Beilstein: 3823291
• EC Number: 213-015-4
• MDL number: MFCD00038940
• UNSPSC 코드: 12352204
• PubChem Substance ID: 24891699
• NACRES: NA.32

속성

• 분석: ≥98% (TLC)
• 양식: powder
• solubility: DMF: 50 mg/mL, clear, colorless to faintly yellow
• 저장 온도: 2-8°C
• SMILES string: Cl[H].NC(=N)NCCCC(NC(=O)c1ccccc1)C(=O)Nc2ccc3ccccc3c2
• InChI: 1S/C23H25N5O2.ClH/c24-23(25)26-14-6-11-20(28-21(29)17-8-2-1-3-9-17)22(30)27-19-13-12-16-7-4-5-10-18(16)15-19;/h1-5,7-10,12-13,15,20H,6,11,14H2,(H,27,30)(H,28,29)(H4,24,25,26);1H
• InChI key: BNGRKDJZQIGWQF-UHFFFAOYSA-N

설명

애플리케이션

N_α-Benzoyl-DL-arginine β-naphthylamide hydrochloride has been used as a substrate in the BANA test to evaluate the inhibitory activity of stefin.[1] It has also been used as a substrate for the determination of Ki values of inhibitors toward trypsin.[2]

생화학적/생리학적 작용

N_α-Benzoyl-DL-arginine β-naphthylamide hydrochloride (BANA) helps to determine the activities of cathepsin B and papain.[3] BANA test is also useful in identifying the number of periodontal sites with periodontal pathogens.[4] Presence of volatile sulfur compounds (VSCs), synthesized by oral bacteria in dental plaque or tongue coating can be colorimetrically confirmed by their ability to hydrolyze N-benzoyl-DL-arginine-2-naphthylamide.[5]

기질

A chromogenic substrate for trypsin.

안전성 정보

• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 3
• Flash Point (°F): Not applicable
• Flash Point (°C): Not applicable
• 개인 보호 장비: Eyeshields, Gloves, type N95 (US)