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Merck
모든 사진(2)

주요 문서

B1814

Sigma-Aldrich

BMP2, human

Carrier Free, ≥98% (SDS-PAGE), recombinant, expressed in E. coli, lyophilized powder, suitable for cell culture

동의어(들):

Bone Morphogenetic Protein 2 human, BMP-2

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About This Item

MDL number:
UNSPSC 코드:
12352202
NACRES:
NA.32

제품명

Bone Morphogenetic Protein 2 human, Carrier Free, ≥98% (SDS-PAGE), recombinant, expressed in E. coli, lyophilized powder, suitable for cell culture

생물학적 소스

human

Quality Level

재조합

expressed in E. coli

분석

≥98% (SDS-PAGE)

양식

lyophilized powder

분자량

26 kDa

포장

pkg of 10 μg

저장 조건

avoid repeated freeze/thaw cycles (Do not store in a frost-free freezer.)

기술

cell culture | mammalian: suitable

불순물

Endotoxin, tested

색상

white

solubility

water: soluble 0.100 mL, clear, colorless

UniProt 수납 번호

저장 온도

−20°C

유전자 정보

human ... BMP2(650)

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생화학적/생리학적 작용

Cellular responses to BMP-2 are mediated by the formation of hetero-oligomeric complexes of type I and type II serine/threonine kinase receptors. BMPs stimulate angiogenesis by inducing the production of VEGF-A by osteoblasts. Human, mouse, and rat BMP-2 demonstrate 100% homology.

물리적 형태

Lyophilized from a 0.2 μm filtered buffered solution.

분석 메모

The biological activity is measured by its ability to induce alkaline phosphatase production by ATDC5 chondrogenic cells.

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point (°F)

104.0 °F - closed cup

Flash Point (°C)

40.0 °C - closed cup


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문서 라이브러리 방문

Lindsay A Bonsignore et al.
Journal of orthopaedic research : official publication of the Orthopaedic Research Society, 33(7), 979-987 (2015-02-14)
The most important factor contributing to short-term and long-term success of cementless total joint arthroplasties is osseointegration. Osseointegration leads to a direct structural and functional connection between living bone and the surface of an implant. Surface contaminants may remain on
Thorsten Pfirrmann et al.
Human molecular genetics, 24(11), 3119-3132 (2015-02-26)
Chordin-Like 1 (CHRDL1) mutations cause non-syndromic X-linked megalocornea (XMC) characterized by enlarged anterior eye segments. Mosaic corneal degeneration, presenile cataract and secondary glaucoma are associated with XMC. Beside that CHRDL1 encodes Ventroptin, a secreted bone morphogenetic protein (BMP) antagonist, the
Ernst B Hunziker et al.
Tissue engineering. Part A, 21(13-14), 2089-2098 (2015-04-22)
The articular cartilage layer of synovial joints is commonly lesioned by trauma or by a degenerative joint disease. Attempts to repair the damage frequently involve the performance of autologous chondrocyte implantation (ACI). Healthy cartilage must be first removed from the
Fengxuan Han et al.
Journal of biomedical materials research. Part B, Applied biomaterials, 103(7), 1344-1353 (2014-11-12)
Repair of cartilage-bone interface tissue remains challenging, because it combines different cell types and gradients of composition and properties. To enable simultaneous regeneration of bone, cartilage, and especially their interface, a conically graded scaffold of chitosan-gelatin hydrogel/poly(l-lactide-co-glycolide) (PLGA) was facilely
Jiho Kang et al.
Journal of periodontal & implant science, 45(3), 101-110 (2015-07-02)
Sclerostin, an inhibitor of Wnt/β-catenin signaling, exerts negative effects on bone formation and contributes to periodontitis-induced alveolar bone loss. Recent studies have demonstrated that serum sclerostin levels are increased in diabetic patients and that sclerostin expression in alveolar bone is

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