A9646
N-Acetylneuraminic acid
from sheep submaxillary glands, ≥99%
동의어(들):
5-Acetamido-3,5-dideoxy-D-glycero-D-galactononulosonic acid, Lactaminic acid, NAN, NANA, Sialic acid
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모든 사진(1)
About This Item
실험식(Hill 표기법):
C11H19NO9
CAS Number:
Molecular Weight:
309.27
Beilstein:
1716283
EC Number:
MDL number:
UNSPSC 코드:
12352201
PubChem Substance ID:
추천 제품
생물학적 소스
sheep submaxillary glands
유형
Type VIII
분석
≥99%
저장 온도
−20°C
SMILES string
O[C@@]1(O[C@@]([C@@H]([C@H](C1)O)NC(C)=O)([H])[C@@H]([C@@H](CO)O)O)C(O)=O
InChI
1S/C11H19NO9/c1-4(14)12-7-5(15)2-11(20,10(18)19)21-9(7)8(17)6(16)3-13/h5-9,13,15-17,20H,2-3H2,1H3,(H,12,14)(H,18,19)/t5-,6+,7+,8+,9+,11-/m0/s1
InChI key
SQVRNKJHWKZAKO-PFQGKNLYSA-N
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생화학적/생리학적 작용
Both sialic acid and neuraminic acid are loosely used to refer to conjugates of neuraminic acid. N-Acetylneuraminic acid is often found as the terminal sugar of cell surface glycoproteins. Cell surface glycoproteins have important roles in cell recognition and interaction as well as in cell adhesion. Membrane glycoproteins are also important in tumor growth and metastases.
Reshmi Parameswaran et al.
The Journal of experimental medicine, 210(4), 805-819 (2013-03-13)
The development of resistance to chemotherapy is a major cause of relapse in acute lymphoblastic leukemia (ALL). Though several mechanisms associated with drug resistance have been studied in detail, the role of carbohydrate modification remains unexplored. Here, we investigated the
Evolution. Great apes and zoonoses.
Paul M Sharp et al.
Science (New York, N.Y.), 340(6130), 284-286 (2013-04-20)
T A Timofeeva et al.
Voprosy virusologii, 58(1), 24-27 (2013-06-22)
The influenza virus hemagglutinin (HA) is an envelope virus glycoprotein responsible for the attachment of the virus particles to cells via binding terminal sialic acid residues of cell surface oligosaccharides. In our previous works on influenza A virus escape mutants
Sasirekha Ramani et al.
Journal of virology, 87(13), 7255-7264 (2013-04-26)
Naturally occurring bovine-human reassortant rotaviruses with a P[11] VP4 genotype exhibit a tropism for neonates. Interaction of the VP8* domain of the spike protein VP4 with sialic acid was thought to be the key mediator for rotavirus infectivity. However, recent
Influenza: Pathways to human adaptation.
David A Steinhauer
Nature, 499(7459), 412-413 (2013-07-19)
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