A2388

N-Acetylneuraminic acid

≥98% (HPLC), from Escherichia coli

• 동의어(들): 5-Acetamido-3,5-dideoxy-D-glycero-D-galactononulosonic acid, Lactaminic acid, NAN, NANA, Sialic acid
• 실험식(Hill 표기법): C₁₁H₁₉NO₉
• CAS Number: 131-48-6
• Molecular Weight: 309.27
• Beilstein: 1716283
• EC Number: 205-023-1
• MDL number: MFCD00006620
• UNSPSC 코드: 12352201
• PubChem Substance ID: 24890650
• NACRES: NA.25

속성

• 생물학적 소스: Escherichia coli
• 유형: Type VI
• 분석: ≥98% (HPLC)
• 형태: powder
• 광학 활성: [α]20/D -34.0 to -30.0 °, c = 1% in water
• 기술: HPLC: suitable
• 색상: white to off-white
• mp: 184-186 °C
• solubility: water: 50 mg/mL, clear, colorless
• 저장 온도: −20°C
• SMILES string: O[C@@]1(O[C@@]([C@@H]([C@H](C1)O)NC(C)=O)([H])[C@@H]([C@@H](CO)O)O)C(O)=O
• InChI: 1S/C11H19NO9/c1-4(14)12-7-5(15)2-11(20,10(18)19)21-9(7)8(17)6(16)3-13/h5-9,13,15-17,20H,2-3H2,1H3,(H,12,14)(H,18,19)/t5-,6+,7+,8+,9+,11-/m0/s1
• InChI key: SQVRNKJHWKZAKO-PFQGKNLYSA-N

설명

애플리케이션

N-Acetylneuraminic acid (NANA, Neu5Ac) is a major component of glycoconjugates such as glycolipids, glycoproteins and proteoglycans (sialogylcoproteins) where it confers selective binding characteristics to the glycosylated component. Neu5Ac is used to study its biochemistry, metabolism and uptake in vivo and in vitro. Neu5Ac is used in the development of nanocarriers.

생화학적/생리학적 작용

Both sialic acid and neuraminic acid are loosely used to refer to conjugates of neuraminic acid. N-Acetylneuraminic acid is often found as the terminal sugar of cell surface glycoproteins. Cell surface glycoproteins have important roles in cell recognition and interaction as well as in cell adhesion. Membrane glycoproteins are also important in tumor growth and metastases.

기타 정보

To gain a comprehensive understanding of our extensive range of Monosaccharides for your research, we encourage you to visit our Carbohydrates Category page.

안전성 정보

• 픽토그램: GHS07
• 신호어: Warning
• 유해 및 위험 성명서: H319
• 예방조치 성명서: P264 - P280 - P305 + P351 + P338 - P337 + P313
• Hazard Classifications: Eye Irrit. 2
• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 2
• Flash Point (°F): Not applicable
• Flash Point (°C): Not applicable
• 개인 보호 장비: Eyeshields, Gloves, type N95 (US)