A5282
DL-2-Amino-5-phosphonopentanoic acid
≥98% (TLC), solid, NMDA receptor antagonist
동의어(들):
5-Phosphono-DL-norvaline, DL-2-Amino-5-phosphonovaleric acid, AP-5, APV
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모든 사진(1)
크기 선택
보기 변경
10 MG
₩205,233
25 MG
₩537,544
50 MG
₩754,044
100 MG
₩1,724,079
About This Item
실험식(Hill 표기법):
C5H12NO5P
CAS Number:
Molecular Weight:
197.13
Beilstein:
2446389
MDL number:
UNSPSC 코드:
12352106
PubChem Substance ID:
NACRES:
NA.32
추천 제품
제품명
DL-2-Amino-5-phosphonopentanoic acid, solid
양식
solid
색상
white
solubility
0.1 M NaOH: 4 mg/mL
H2O: 5.6 mg/mL
organic solvents: insoluble
SMILES string
NC(CCCP(O)(O)=O)C(O)=O
InChI
1S/C5H12NO5P/c6-4(5(7)8)2-1-3-12(9,10)11/h4H,1-3,6H2,(H,7,8)(H2,9,10,11)
InChI key
VOROEQBFPPIACJ-UHFFFAOYSA-N
유전자 정보
rat ... Grik1(29559) , Grin2a(24409) , Grin2b(24410)
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애플리케이션
DL-2-Amino-5-phosphonopentanoic acid has been used:
- in the inactivation of N-methyl-D-aspartate (NMDA)-mediated synapses[1]
- used in growth medium for inhibition of electrical activity in the neuronal network[2]
- used to isolate N-methyl-D-aspartate receptors (NMDAR) or α-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid receptor (AMPAR)-mediated currents were isolated using this product[3]
- used in double distilled water to compare its NMDA antagonistic action with that of prion protein (PrPC)[4]
생화학적/생리학적 작용
Anticonvulsant; potent and selective NMDA receptor antagonist.
주의사항
Hygroscopic
신호어
Warning
유해 및 위험 성명서
Hazard Classifications
Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
표적 기관
Respiratory system
Storage Class Code
11 - Combustible Solids
WGK
WGK 3
Flash Point (°F)
Not applicable
Flash Point (°C)
Not applicable
개인 보호 장비
dust mask type N95 (US), Eyeshields, Gloves
가장 최신 버전 중 하나를 선택하세요:
시험 성적서(COA)
Lot/Batch Number
이미 열람한 고객
Activation of NR2A-containing NMDA receptors is not obligatory for NMDA receptor-dependent long-term potentiation
Weitlauf C, et al.
The Journal of Neuroscience, 25(37), 8386-8390 (2005)
Engineered neuronal circuits shaped and interfaced with carbon nanotube microelectrode arrays
Shein M, et al.
Biomedical Microdevices, 11(2), 495-501 (2009)
Ryota Kobayashi et al.
Frontiers in computational neuroscience, 3, 9-9 (2009-08-12)
Information is transmitted in the brain through various kinds of neurons that respond differently to the same signal. Full characteristics including cognitive functions of the brain should ultimately be comprehended by building simulators capable of precisely mirroring spike responses of
Marijn van Wingerden et al.
Neuron, 76(4), 813-825 (2012-11-28)
Neural activity in orbitofrontal cortex has been linked to flexible representations of stimulus-outcome associations. Such value representations are known to emerge with learning, but the neural mechanisms supporting this phenomenon are not well understood. Here, we provide evidence for a
Bence P Olveczky et al.
PLoS biology, 3(5), e153-e153 (2005-04-14)
Songbirds learn their songs by trial-and-error experimentation, producing highly variable vocal output as juveniles. By comparing their own sounds to the song of a tutor, young songbirds gradually converge to a stable song that can be a remarkably good copy
활성 필터
자사의 과학자팀은 생명 과학, 재료 과학, 화학 합성, 크로마토그래피, 분석 및 기타 많은 영역을 포함한 모든 과학 분야에 경험이 있습니다..
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