모든 사진(1)
About This Item
Linear Formula:
H2NC3H4CO2H·HCl
CAS Number:
Molecular Weight:
137.56
MDL number:
UNSPSC 코드:
12352209
PubChem Substance ID:
추천 제품
분석
≥98%
양식
powder
mp
231 °C (dec.) (lit.)
SMILES string
Cl.NC1(CC1)C(O)=O
InChI
1S/C4H7NO2.ClH/c5-4(1-2-4)3(6)7;/h1-2,5H2,(H,6,7);1H
InChI key
WTZRHZRMLYNBRM-UHFFFAOYSA-N
유전자 정보
human ... GRIN1(2902) , GRINA(2907)
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생화학적/생리학적 작용
1-Aminocyclopropanecarboxylic acid hydrochloride (ACPC) contains 3-membered carbocyclic rings and is a cyclic homolog of glycine. It acts as an agonist of the N-methyl-D-aspartate (NMDA) receptor.[1] It elicits protection against glutamate-induced neurotoxicity in neurons.[2]
NMDA glutamate receptor agonist acting at the glycine site
신호어
Warning
유해 및 위험 성명서
Hazard Classifications
Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
표적 기관
Respiratory system
Storage Class Code
11 - Combustible Solids
WGK
WGK 3
Flash Point (°F)
Not applicable
Flash Point (°C)
Not applicable
개인 보호 장비
dust mask type N95 (US), Eyeshields, Gloves
Synan Abuqamar et al.
The Plant cell, 20(7), 1964-1983 (2008-07-05)
The tomato protein kinase 1 (TPK1b) gene encodes a receptor-like cytoplasmic kinase localized to the plasma membrane. Pathogen infection, mechanical wounding, and oxidative stress induce expression of TPK1b, and reducing TPK1b gene expression through RNA interference (RNAi) increases tomato susceptibility
Yunpeng Wang et al.
The international journal of neuropsychopharmacology, 20(7), 562-574 (2017-02-16)
Opiate addiction is associated with complex cognitive impairment, which contributes to the development of compulsive drug use and relapses. Dopamine and N-methyl-D-aspartate receptors play critical roles in opiate-induced cognitive deficits. However, the roles of D1 and D3 receptors in the
Susanne Weis et al.
Brain and cognition, 131, 66-73 (2017-10-17)
It has not yet been established if resting state (RS) connectivity reflects stable characteristics of the brain, or if it is modulated by the psychological and/or physiological state of the participant. Based on research demonstrating sex hormonal effects in task-related
1-Aminocyclopropanecarboxylic acid, an antagonist of N-methyl-D-aspartate receptors, causes hypotensive and antioxidant effects with upregulation of heme oxygenase-1 in stroke-prone spontaneously hypertensive rats.
Gao, et al.
Hypertension Research, 30, 249-257 (2016)
Alan Anticevic et al.
Schizophrenia bulletin, 41(1), 133-143 (2014-05-02)
Bipolar illness is a debilitating neuropsychiatric disorder associated with alterations in the ventral anterior cingulate cortex (vACC), a brain region thought to regulate emotional behavior. Although recent data-driven functional connectivity studies provide evidence consistent with this possibility, the role of
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