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Merck
모든 사진(1)

주요 문서

A023

Sigma-Aldrich

2-(Methylthio)adenosine 5′-triphosphate tetrasodium salt hydrate

solid, ≥90%

동의어(들):

2-MeSATP, 2-Methylthio-ATP tetrasodium salt hydrate

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About This Item

실험식(Hill 표기법):
C11H14N5Na4O13P3S · xH2O
Molecular Weight:
641.20 (anhydrous basis)
MDL number:
UNSPSC 코드:
12352200
PubChem Substance ID:
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분석

≥90%

양식

solid

저장 조건

desiccated

색상

white

solubility

H2O: 13 mg/mL (Solutions should be freshly prepared.)

εmax

15,100 at 274 nm
20,900 at 233.4 nm

배송 상태

dry ice

저장 온도

−70°C

SMILES string

[Na+].[Na+].[Na+].[Na+].CSc1nc(N)c2ncn([C@@H]3O[C@H](COP([O-])(=O)OP([O-])(=O)OP([O-])([O-])=O)[C@@H](O)[C@H]3O)c2n1

InChI

1S/C11H18N5O13P3S.4Na/c1-33-11-14-8(12)5-9(15-11)16(3-13-5)10-7(18)6(17)4(27-10)2-26-31(22,23)29-32(24,25)28-30(19,20)21;;;;/h3-4,6-7,10,17-18H,2H2,1H3,(H,22,23)(H,24,25)(H2,12,14,15)(H2,19,20,21);;;;/q;4*+1/p-4/t4-,6-,7-,10-;;;;/m1..../s1

InChI key

UEEFBRHXFDJPTA-KWIZKVQNSA-J

유사한 제품을 찾으십니까? 방문 제품 비교 안내

생화학적/생리학적 작용

2-Methylthioadenosine triphosphate is a potent P2Y purinoceptor agonist.

주의사항

Hygroscopic.

Storage Class Code

13 - Non Combustible Solids

WGK

WGK 3

Flash Point (°F)

Not applicable

Flash Point (°C)

Not applicable

개인 보호 장비

Eyeshields, Gloves, type N95 (US)


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문서 라이브러리 방문

Peter D J Thornton et al.
PloS one, 8(2), e40840-e40840 (2013-02-06)
The nature of synaptic transmission at functionally distinct synapses in intestinal reflex pathways has not been fully identified. In this study, we investigated whether transmission between interneurons in the descending inhibitory pathway is mediated by a purine acting at P2Y
Melanie J Ludlow et al.
Cell calcium, 44(6), 567-579 (2008-05-20)
The presence of five P2X-like genes (p2xA-E) in Dictyostelium suggests that nucleotides other than cAMP may act as extracellular signalling molecules in this model eukaryote. However, p2xA was found to have an exclusively intracellular localisation making it unclear whether Dictyostelium
R Preston Mason et al.
BMC pharmacology & toxicology, 14, 48-48 (2013-10-01)
Nebivolol is a third-generation beta-blocker used to treat hypertension. The vasodilation properties of nebivolol have been attributed to nitric oxide (NO) release. However, the kinetics and mechanism of nebivolol-stimulated bioavailable NO are not fully understood. Using amperometric NO and peroxynitrite
N J Cusack et al.
British journal of pharmacology, 75(2), 397-400 (1982-02-01)
Some 2-alkylthio derivatives of adenosine 5'-monophosphate (AMP), adenosine 5'-monophosphorothioate (AMPS) and adenosine 5'-triphosphate (ATP) were examined as inhibitors of human platelet aggregation. 2-Methylthio-AMP, 2-ethylthio-AMP, 2-(pentan-l-yl)thio-AMP, 2-ethylthio-AMPS, 2-methylthio-ATP and 2-ethylthio-ATP (100 microM) each inhibited aggregation induced by adenosine 5'-diphosphate (ADP) but
Takayuki Ohnishi et al.
Molecular pain, 5, 40-40 (2009-07-22)
The translocation of neuronal nitric oxide synthase (nNOS) from the cytosol to the membrane is functionally coupled to the activation of N-methyl-D-aspartate (NMDA) receptors at synapses. Whereas there is abundant evidence indicating that ATP and nitric oxide are involved in

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