46985

Fluorescein-5-thiosemicarbazide

suitable for fluorescence, ~80% (HPCE)

• 실험식(Hill 표기법): C₂₁H₁₅N₃O₅S
• CAS Number: 76863-28-0
• Molecular Weight: 421.43
• MDL number: MFCD00155658
• UNSPSC 코드: 12352125
• PubChem Substance ID: 329757284
• NACRES: NA.32

속성

• 분석: ~80% (HPCE)
• 양식: solid
• solubility: DMF: soluble; H₂O: soluble
• 형광: λ_ex 492 nm; λ_em 516 nm in 0.1 M Tris pH 9.0
• 적합성: suitable for fluorescence
• 저장 온도: −20°C
• SMILES string: NNC(=S)Nc1ccc(c(c1)C(O)=O)C2=C3C=CC(=O)C=C3Oc4cc(O)ccc24
• InChI: 1S/C21H15N3O5S/c22-24-21(30)23-10-1-4-13(16(7-10)20(27)28)19-14-5-2-11(25)8-17(14)29-18-9-12(26)3-6-15(18)19/h1-9,25H,22H2,(H,27,28)(H2,23,24,30)
• InChI key: MEUCHQDLZYLNQY-UHFFFAOYSA-N

설명

일반 설명

Fluorescein-5-thiosemicarbazide, also known as FTC, is a fluorescent probe.[1] The FTSC fluorescent spectra is like FITC, a preferred fluorescent tag for proteomics. The fluorescence spectral properties of FTSC-labeled vesicles obtained by reductive amination are fully compatible with the argon laser of fluorescent instruments.[2]

애플리케이션

Fluorescein-5-thiosemicarbazide can be used as a fluorescent labeling reagent to label:

• Cell-surface functional groups (glycophorins) in the study of the effect of deoxygenation in the red blood cell membrane.[3]
• Saccharides applicable in polysaccharide imaging in live cells.[4]
• Chondroitin sulfate nanogels applicable in cell-specific drug delivery applications.[5]

특징 및 장점

Fluorescein-5-thiosemicarbazide has the following benefits -

• It displays strong fluorescence property.[2]
• Shows an intrinsic reactivity of the thiosemicarbazide group towards the aldehyde group.[2]

안전성 정보

• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 3
• Flash Point (°F): Not applicable
• Flash Point (°C): Not applicable
• 개인 보호 장비: Eyeshields, Gloves, type N95 (US)