451M-1

h-Caldesmon (hHCD) Mouse Monoclonal Antibody

• UNSPSC 코드: 12352203

속성

• 생물학적 소스: mouse
• Quality Level: 100; 500
• 결합: unconjugated
• 항체 형태: diluted ascites fluid
• 항체 생산 유형: primary antibodies
• 클론: hHCD, monoclonal
• 설명: For In Vitro Diagnostic Use in Select Regions
• 양식: buffered aqueous solution
• 종 반응성: human
• 포장: vial of 0.1 mL concentrate (451M-14); vial of 0.1 mL concentrate Research Use Only (451M-14-RUO); vial of 0.5 mL concentrate (451M-15); vial of 1.0 mL concentrate (451M-16); vial of 1.0 mL concentrate Research Use Only (451M-16-RUO); vial of 1.0 mL pre-dilute Research Use Only (451M-17-RUO); vial of 1.0 mL pre-dilute ready-to-use (451M-17); vial of 7.0 mL pre-dilute ready-to-use (451M-18); vial of 7.0 mL pre-dilute ready-to-use Research Use Only (451M-18-RUO)
• 제조업체/상표: Cell Marque^®
• 기술: immunohistochemistry (formalin-fixed, paraffin-embedded sections): 1:50-1:100 (concentrated)
• 동형: IgG1
• 제어: bladder, colon, leiomyoma, smooth muscle tumors, stomach
• 배송 상태: wet ice
• 저장 온도: 2-8°C
• 시각화: cytoplasmic

설명

일반 설명

Caldesmon is a protein that facilitates the regulation of cellular contraction through complexing with calmodulin, tropomyosin, and actin. Its high molecular weight isoform (h-caldesmon) has been identified to have restricted expression in visceral and vascular smooth muscle cells. In particular, strong expression of h-caldesmon has been observed in non-neoplastic uterine myometrium while being entirely absent in the endometrial layer.[1] In spindle cell tumor pathology, overlapping immunohistochemical staining profiles between smooth muscle cells and myofibroblastic cells has not allowed for reliable identification of true smooth muscle tumors. Immunohistochemical detection of h-caldesmon has been demonstrated to aid in the distinguishing smooth muscle tumors, such as leiomyoma and leiomyosarcoma from myofibroblastic lesions, such as inflammatory myofibroblastic tumors and fibromatoses.[2]

품질

IVD

IVD

IVD

RUO

물리적 형태

Solution in Tris Buffer, pH 7.3-7.7, with 1% BSA and <0.1% Sodium Azide.

제조 메모

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기타 정보

For Technical Service please contact: 800-665-7284 or email: [email protected]

법적 정보

Cell Marque is a registered trademark of Merck KGaA, Darmstadt, Germany

안전성 정보

• Storage Class Code: 12 - Non Combustible Liquids
• WGK: WGK 2